FIGURE: 1 / 3
A suggested positive control is mouse lung tissue lysate.
PA5-21137 can be used with blocking peptide PEP-1251.
EZH1 is a component of a noncanonical Polycomb repressive complex-2 (PRC2) that mediates methylation of histone H3 lys27 (H3K27) and functions in the maintenance of embryonic stem cell pluripotency and plasticity (Shen et al., 2008 ).
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Protein Aliases: Enhancer of zeste homolog 1; ENX-2; Histone-lysine N-methyltransferase EZH1
Gene Aliases: ENX-2; Enx2; EZH1; KIAA0388; KMT6B
Molecular Function: histone modifying enzyme