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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 1 and 44 of Human EZH1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-28710 targets EZH1 in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-28710 immunogen is synthetic peptide corresponding to a region within amino acids 1 and 44 of Human EZH1.
EZH1 is a component of a noncanonical Polycomb repressive complex-2 (PRC2) that mediates methylation of histone H3 (see MIM 602812) lys27 (H3K27) and functions in the maintenance of embryonic stem cell pluripotency and plasticity (Shen et al., 2008 [PubMed 19026780]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Enhancer of zeste homolog 1; ENX-2; Histone-lysine N-methyltransferase EZH1; KMT6B
EZH1; KIAA0388; KMT6B