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Egr1 Polyclonal Antibody

View all (32) EGR1 antibodies

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Egr1 Polyclonal Antibody

Product Details

BS-1076R

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500
-

Immunohistochemistry (Paraffin) (IHC (P))

1:200
-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-

Flow Cytometry (Flow)

1:20-1:100
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human Egr-1, amino acids 401-453.
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Amount

100 µg

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: AT225; Early growth response protein 1; EGR-1; ETR103; Krox-24 nuclear protein; Nerve growth factor-induced protein A; NGFI-A; Transcription factor ETR103; Transcription factor Zif268; unnamed protein product; zinc finger gene 225; Zinc finger protein 225; Zinc finger protein Krox-24

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Gene Aliases: A530045N19Rik; AT225; egr; Egr-1; EGR1; ETR103; G0S30; Krox-1; KROX-24; KROX24; Ngf1; NGF1-A; Ngfi; NGFI-A; NGFIA; TIS8; Zenk; Zfp-6; ZIF-268; ZIF268; ZNF225

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UniProt ID: (Human) P18146, (Rat) P08154, (Mouse) P08046

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Entrez Gene ID: (Human) 1958, (Rat) 24330, (Mouse) 13653

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Function(s)
transcription regulatory region sequence-specific DNA binding RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding zinc ion binding double-stranded methylated DNA binding enzyme binding histone acetyltransferase binding sequence-specific DNA binding hemi-methylated DNA-binding metal ion binding sequence-specific double-stranded DNA binding promoter-specific chromatin binding RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding double-stranded DNA binding transcription factor binding transcription regulatory region DNA binding nucleic acid binding C2H2 zinc finger transcription factor
Process(es)
negative regulation of transcription from RNA polymerase II promoter response to hypoxia response to ischemia regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter response to glucose positive regulation of gene expression T cell differentiation BMP signaling pathway positive regulation of chemokine production positive regulation of interleukin-1 beta production response to insulin circadian regulation of gene expression regulation of protein sumoylation skeletal muscle cell differentiation regulation of apoptotic process regulation of neuron apoptotic process hypomethylation of CpG island estrous cycle locomotor rhythm positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of hormone biosynthetic process rhythmic process circadian temperature homeostasis interleukin-1-mediated signaling pathway cellular response to gamma radiation cellular response to heparin cellular response to mycophenolic acid glomerular mesangial cell proliferation positive regulation of glomerular metanephric mesangial cell proliferation negative regulation of canonical Wnt signaling pathway cellular response to interleukin-8 positive regulation of post-translational protein modification positive regulation of pri-miRNA transcription from RNA polymerase II promoter regulation of progesterone biosynthetic process response to amphetamine transcription from RNA polymerase II promoter learning or memory circadian rhythm positive regulation of cell death response to nutrient levels response to follicle-stimulating hormone cellular response to insulin stimulus response to carbon monoxide response to gonadotropin cellular response to drug response to cocaine response to drug negative regulation of apoptotic process positive regulation of neuron apoptotic process response to ethanol regulation of long-term neuronal synaptic plasticity oligodendrocyte differentiation response to electrical stimulus long-term synaptic potentiation regulation of transcription from RNA polymerase II promoter in response to hypoxia cellular response to antibiotic cellular response to mechanical stimulus cellular response to organic substance cellular response to isoquinoline alkaloid cellular response to cAMP cellular response to growth factor stimulus cellular response to gonadotropin stimulus cellular response to follicle-stimulating hormone stimulus cellular response to steroid hormone stimulus cellular response to hyperoxia cellular response to hypoxia response to norepinephrine transcription, DNA-templated
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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