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Fabgennix
Elf4/MEF Polyclonal Antibody, FITC
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Product Details
ELF4-FITC
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken within amino acid region 605-655 on mouse ETS-related transcription factor Elf-4 protein.
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
ELF4 is transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. The protein acts synergistically with RUNX1 to transactivate the IL3 promoter. Also transactivates the PRF1 promoter in natural killer (NK) cells. This protein plays a role in the development and function of NK and NK T-cells and in innate immunity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E74-like factor 4; E74-like factor 4 (ets domain transcription factor); E74-like factor 4; myeloid elf-1-like factor; myeloid elf-1 like factor; elf4; ETS-related transcription factor Elf-4; myeloid elf-1 like factor; Myeloid Elf-1-like factor
Gene Aliases: AIFBL2; AV314029; BC042423; ELF4; ELFR; ENSMUSG00000053512; Gm9907; MEF; RGD1560743
UniProt ID: (Human) Q99607, (Mouse) Q9Z2U4
Entrez Gene ID: (Human) 2000, (Mouse) 56501, (Rat) 302811
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
winged helix/forkhead transcription factor
natural killer cell proliferation
NK T cell proliferation
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
cell differentiation
negative regulation of interleukin-1 beta production
negative regulation of interleukin-6 production
negative regulation of tumor necrosis factor production
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of inflammatory response
transcription, DNA-templated
transcription from RNA polymerase II promoter
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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