In direct ELISAs and Western blots, approximately 25% cross-reactivity with recombinant human Endocan is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Endothelial cell-specific molecule 1 is a protein that in humans is encoded by the ESM1 gene. This gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals. Two transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: endocan; Endothelial cell-specific molecule 1; ESM-1; ESM1; IGFBP-rp6
Gene Aliases: 0610042H23Rik; AV004503; ESM-1; Esm1
UniProt ID: (Mouse) Q9QYY7
Entrez Gene ID: (Mouse) 71690