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Bioss
Endothelial Lipase Polyclonal Antibody
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Product Details
BS-10188R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
recombinanted human Endothelial lipase, amino acids 1-500.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
LIPG (Lipase G, Endohelial type) is an endothelial lipase which is a novel member of the lipoprotein lipase gene family. LIPG is synthesized by endothelial cells and functions at the site of synthesis. LIPG most likely plays a physiological role in modulating lipoprotein metabolism. Overexpressed LIPG has been shown to reduce HDL cholesterol levels, whereas an LIPG deficiency appears to be effective in elevating HDL cholesterol levels in animals. LIPG has substantial phospholipase activity and may be involved in lipoprotein metabolism and vascular biology. Also, LIPG is designated a member of the TG lipase family by its sequence and characteristic lid region which provides substrate specificity for enzymes of the TG lipase family. LIPG is a carboxyl esterase that hydrolyzes high density lipoproteins, emulsifies triglycerides, is essential for the efficient digestion of dietary fats and can bind to heparin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EDL; Endothelial cell-derived lipase; Endothelial lipase; lipase, endothelial; lipoprotein lipase H; lipose, endothelial; Phospholipase A1; PL
Gene Aliases: 3110013K01Rik; EDL; EL; lipase; LIPG; mEDL; PRO719; UNQ387/PRO719
UniProt ID: (Human) Q9Y5X9, (Mouse) Q9WVG5
Entrez Gene ID: (Human) 9388, (Mouse) 16891
lipid metabolic process
response to nutrient
cell proliferation
phospholipid catabolic process
positive regulation of high-density lipoprotein particle clearance
positive regulation of cholesterol transport
high-density lipoprotein particle remodeling
cholesterol homeostasis
reverse cholesterol transport
lipid digestion
regulation of lipoprotein metabolic process
phospholipid homeostasis
lipid catabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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