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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 363 and 427 of Human Endothelin A Receptor|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-30589 targets Endothelin A Receptor in IHC (P) and WB applications and shows reactivity with Human and mouse samples.
The PA5-30589 immunogen is synthetic peptide corresponding to a region within amino acids 363 and 427 of Human Endothelin A Receptor.
This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
endothelin A receptor; endothelin receptor subtype A; endothelin-1 receptor; endothelin-1-specific receptor; ET-A; ETA; ETA-R; ETAR; ETRA; G protein-coupled receptor; G-protein coupled receptor 10; hET-AR
EDNRA; ET-A; ET-AR; ETA; ETA-R; ETAR; ETRA; Gpcr10; hET-AR; MFDA