Recommended positive controls: U87-MG, GL261.
Predicted reactivity: Rhesus Monkey (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants.
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Protein Aliases: endothelin A receptor; endothelin receptor subtype A; Endothelin receptor type A; Endothelin-1 receptor; endothelin-1-specific receptor; ET-A; ETA; ETA-R; ETAR; ETRA; G protein-coupled receptor; G-protein coupled receptor 10; hET-AR
Gene Aliases: EDNRA; Endor; ET-A; ET-AR; ETA; ETA-R; ETAR; ETRA; Gpcr10; hET-AR; MFDA; RGD1559432