Recommended positive controls: Jurkat, Raji.
Predicted reactivity: Mouse (97%), Rat (96%), Pig (97%), Chicken (92%), Bovine (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
EPHA3 (EPA receptor A3), also known as ETK, HEK, ETK1, HEK4, TYRO4, is belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 binds ephrin-A ligands.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EK4; EPH-like kinase 4; Eph-like tyrosine kinase 1; Ephrin type-A receptor 3; H TYRO4; HEK; Human embryo kinase; human embryo kinase 1; testicular tissue protein Li 64; TYRO4 protein tyrosine kinase; Tyrosine-protein kinase receptor ETK1; Tyrosine-protein kinase TYRO4
Gene Aliases: EK4; EPHA3; ETK; ETK1; HEK; HEK4; TYRO4
UniProt ID: (Human) P29320
Entrez Gene ID: (Human) 2042