PA5-29338 targets Eph receptor A4 in WB applications and shows reactivity with Human samples.
The PA5-29338 immunogen is recombinant fragment corresponding to a region within amino acids 430 and 766 of Human Eph receptor A4.
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This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
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Protein Aliases: EK8; EPH-like kinase 8; Ephrin type-A receptor 4; HEK8; receptor protein-tyrosine kinase HEK8; SEK; TYRO1; TYRO1 protein tyrosine kinase; Tyrosine-protein kinase receptor SEK; Tyrosine-protein kinase TYRO1
Gene Aliases: EPHA4; HEK8; SEK; TYRO1
UniProt ID: (Human) P54764
Entrez Gene ID: (Human) 2043