This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Recommended positive controls: HeLa, 293T, mouse brain, mouse hippocampus, rat brain, A2058, DDDDK-tagged EPHA4-transfected 293T.
Predicted reactivity: Mouse (100%), Rat (99%), Xenopus laevis (92%), Pig (99%), Chicken (96%), Rhesus Monkey (100%).
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These proteins belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands.
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Protein Aliases: EK8; epa4; EPH-like kinase 8; Ephrin type-A receptor 4; receptor protein-tyrosine kinase HEK8; TYRO1 protein tyrosine kinase; Tyrosine-protein kinase receptor MPK-3; Tyrosine-protein kinase receptor SEK; Tyrosine-protein kinase receptor SEK-1; Tyrosine-protein kinase TYRO1
Gene Aliases: 2900005C20Rik; AI385584; Cek8; EPHA4; HEK8; rb; RGD1560587; SEK; Sek1; TYRO1