Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset (100%); Dog, Panda, Horse (94%); Bovine, Bat, Hamster, Elephant, Pig, Opossum, Turkey, Chicken (88%); Mouse, Rat, Rabbit, Platypus, Lizard, Xenopus (81%).
For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
EPHA4 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EphA4 encodes a protein that binds ephrin-A ligands.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EK8; epa4; EPH-like kinase 8; Ephrin type-A receptor 4; receptor protein-tyrosine kinase HEK8; TYRO1 protein tyrosine kinase; Tyrosine-protein kinase receptor SEK; Tyrosine-protein kinase TYRO1
Gene Aliases: EPHA4; HEK8; SEK; TYRO1
UniProt ID: (Human) Q2M380
Entrez Gene ID: (Human) 2043
Molecular Function: transmembrane signal receptor
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