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Invitrogen
EphA7 Polyclonal Antibody
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Product Details
PA1-28012
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Purified recombinant mouse EphA7 extracellular domain.
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
25 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 5% trehalose
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
PA1-28012 detects EphA7 from mouse samples.
Target Information
EPHA7 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system. EPHA7 is involved in embryonic development. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Developmental kinase 1; EBK; EHK-3; Embryonic brain kinase; epa7; EPH homology kinase 3; EPHA7-S; Ephrin type-A receptor 7; mDK-1
Gene Aliases: Cek11; Ebk; Ehk3; Epha7; Hek11; Mdk1
UniProt ID: (Mouse) Q61772
Entrez Gene ID: (Mouse) 13841
nucleotide binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
ephrin receptor activity
GPI-linked ephrin receptor activity
protein binding
ATP binding
axon guidance receptor activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
chemorepellent activity
ephrin receptor binding
transmembrane signal receptor
protein phosphorylation
apoptotic process
signal transduction
transmembrane receptor protein tyrosine kinase signaling pathway
multicellular organism development
nervous system development
brain development
phosphorylation
peptidyl-tyrosine phosphorylation
regulation of cell-cell adhesion
retinal ganglion cell axon guidance
regulation of protein autophosphorylation
positive regulation of apoptotic process
regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of neuron apoptotic process
ephrin receptor signaling pathway
branching morphogenesis of a nerve
regulation of peptidyl-tyrosine phosphorylation
negative chemotaxis
regulation of ERK1 and ERK2 cascade
nephric duct morphogenesis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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