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Invitrogen
EphA7 Polyclonal Antibody
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Product Details
PA1-30296
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 896-925 amino acids from the C-terminal region of human EphA7.
Conjugate
Form
Liquid
Concentration
2 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Control: NCl-H460 cell lysate.
Target Information
EPHA7 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system. EPHA7 is involved in embryonic development. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: EHK-3; EK11; epa7; EPH homology kinase 3; Eph homology kinase-3; EPH-like kinase 11; EPHA7-S; Ephrin type-A receptor 7; receptor protein-tyrosine kinase HEK11; tyrosine-protein kinase receptor EHK-3
Gene Aliases: EHK-3; EHK3; EK11; EPHA7; HEK11
UniProt ID: (Human) Q15375
Entrez Gene ID: (Human) 2045
positive regulation of protein phosphorylation
apoptotic process
brain development
phosphorylation
peptidyl-tyrosine phosphorylation
regulation of cell-cell adhesion
retinal ganglion cell axon guidance
regulation of protein autophosphorylation
regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of neuron apoptotic process
ephrin receptor signaling pathway
negative regulation of collateral sprouting
branching morphogenesis of a nerve
regulation of peptidyl-tyrosine phosphorylation
negative chemotaxis
negative regulation of synapse assembly
regulation of ERK1 and ERK2 cascade
nephric duct morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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