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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:200-1:2,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 300-540 of human EPHB4. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.39 mg/mL |
Purification |
Affinity Chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2808042 |
Immunogen sequence: AVCQCRVGYF RARTDPRGAP CTTPPSAPRS VVSRLNGSSL HLEWSAPLES GGREDLTYAL RCRECRPGGS CAPCGGDLTF DPGPRDLVEP WVVVRGLRPD FTYTFEVTAL NGVSSLATGP VPFEPVNVTT DREVPPAVSD IRVTRSSPSS LSLAWAVPRA PSGAVLDYEV KYHEKGAEGP SSVRFLKTSE NRAELRGLKR GASYLVQVRA RSEAGYGPFG QEHHSQTQLD ESEGWREQLA L; Positive Samples: Mouse liver; Cellular Location: Cell membrane, Single-pass type I membrane protein
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CAPB; Developmental kinase 2; DRT; EPHB2; EPHB3; Ephrin B1; Ephrin B2; Ephrin B3; Ephrin B4; ephrin receptor EphB4; Ephrin type-B receptor 4; EphrinB1; EphrinB2; EphrinB3; EphrinB4; EPHT3; ERK; ETK2; HEK-6; HEK2; Hek5; Hepatoma transmembrane kinase; mDK-2; MGC87492; PCBC; soluble EPHB4 variant 1; soluble EPHB4 variant 2; soluble EPHB4 variant 3; Tyro5; TYRO6; Tyrosine kinase MYK-1; tyrosine-protein kinase receptor HTK; Tyrosine-protein kinase TYRO11
Gene Aliases: AI042935; EPHB4; HTK; MDK2; MYK1; TYRO11
UniProt ID: (Human) P54760, (Mouse) P54761
Entrez Gene ID: (Human) 2050, (Mouse) 13846
Molecular Function:
transmembrane signal receptor
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