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Invitrogen
Ephrin B2 Polyclonal Antibody
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FIGURE: 1 / 38
Ephrin B2 Antibody (PA5-106933) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded Ephrin B2 in human meningeal carcinomatosis(MC) tissue sections. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with Ephrin B2 polyclonal antibody (Product # PA5-106933) using a dilution of 1:200 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-106933
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human EFNB2(Accession P52799), corresponding to amino acid residues Y304-V333.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total Ephrin B2.
Target Information
This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Efnb2; EPH-related receptor tyrosine kinase ligand 5; HTK ligand; ligand of eph-related kinase 5; ligand of the eph-related receptor tyrosine kinases hek and elk; membrane protein; MGC126226; MGC126227; MGC126228; unnamed protein product
Gene Aliases: ELF-2; ephrin-B2; Epl5; EPLG5; Htk-L; HTKL; LERK-5; LERK5; NLERK-1
UniProt ID: (Human) P52799, (Mouse) P52800
Entrez Gene ID: (Human) 1948, (Rat) 306636, (Mouse) 13642
angiogenesis
lymph vessel development
cell migration involved in sprouting angiogenesis
cell adhesion
axon guidance
positive regulation of cell proliferation
organ morphogenesis
negative regulation of keratinocyte proliferation
negative regulation of neuron projection development
T cell costimulation
adherens junction organization
ephrin receptor signaling pathway
blood vessel morphogenesis
anatomical structure formation involved in morphogenesis
venous blood vessel morphogenesis
regulation of chemotaxis
cellular response to lipopolysaccharide
nephric duct morphogenesis
presynapse assembly
regulation of postsynaptic membrane neurotransmitter receptor levels
regulation of postsynaptic neurotransmitter receptor internalization
positive regulation of aorta morphogenesis
positive regulation of leukocyte adhesion to arterial endothelial cell
positive regulation of cardiac muscle cell differentiation
anatomical structure morphogenesis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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