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Fabgennix
Ephrin Receptor A1 Polyclonal Antibody
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Product Details
EPHAR1-101AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken within amino acid region 55-605 on human Ephrin type-A receptor 1.
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
EphA1 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EphA1 is expressed in some human cancer cell lines and has been implicated in carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EPH tyrosine kinase; EPH tyrosine kinase 1; Ephrin type-A receptor 1; erythropoietin-producing hepatoma amplified sequence; Erythropoietin-producing hepatoma receptor; hEpha1; MGC163163; oncogene EPH; tyrosine kinase receptor precursor (put.); putative; Tyrosine-protein kinase receptor EPH; unnamed protein product
Gene Aliases: EPH; EPHA1; EPHT; EPHT1
UniProt ID: (Human) P21709
Entrez Gene ID: (Human) 2041
angiogenesis
positive regulation of cell-matrix adhesion
cell adhesion
transmembrane receptor protein tyrosine kinase signaling pathway
regulation of cell adhesion
positive regulation of cell migration
negative regulation of cell migration
substrate adhesion-dependent cell spreading
positive regulation of angiogenesis
ephrin receptor signaling pathway
positive regulation of stress fiber assembly
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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