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Bioss
Epigen Polyclonal Antibody
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Product Details
BS-5767R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human Epigen, amino acids 51-130.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Epigen is an EGF-related polypeptide growth factor that signals through the ErbB receptor-1. Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases. It is produced in several tissues, including the testis, liver, and heart, as well as in certain tumor cells. Epigen is mitogenic for fibroblasts and epithelial cells. Human Epigen is initially synthesized as a glycosylated 14.7 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a mature soluble sequence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EPG; Epigen; Epithelial mitogen; epithelial mitogen homolog; growth factor; intracellular protein; secreted protein; unnamed protein product
Gene Aliases: 2310069M11Rik; ALGV3072; EPG; EPGN; epigen; PRO9904; RGD1560084; UNQ3072/PRO9904
UniProt ID: (Human) Q6UW88, (Mouse) Q924X1
Entrez Gene ID: (Human) 255324, (Rat) 289515, (Mouse) 71920
MAPK cascade
angiogenesis
cell surface receptor signaling pathway
epidermal growth factor receptor signaling pathway
positive regulation of cell proliferation
positive regulation of MAPK cascade
positive regulation of mitotic nuclear division
positive regulation of epithelial cell proliferation
activation of MAPK activity
biological_process
positive regulation of MAP kinase activity
positive regulation of epidermal growth factor-activated receptor activity
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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