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          • Primary Antibodies ›
          • Epsin 2 Antibodies

          Bioss

          Epsin2B Polyclonal Antibody

          View all (18) Epsin 2 antibodies

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          Cite Epsin2B Polyclonal Antibody

          Additional Information:
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          Product Details

          BS-9485R

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          Assay-dependent
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          KLH conjugated synthetic peptide derived from human ENTHD1/Epsin2B.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Protein A

          Storage buffer

          0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

          Contains

          0.02% ProClin 300

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          Epsin2 plays a role in the formation of clathrin-coated invaginations and endocytosis. It binds to EPS15 (via the NPF repeat domain), as well as to AP-2 and clathrin (via the DPW repeat domain). The protein resides in the cytoplasm, in punctate structures throughout the cell, associated with clathrin-coated vesicles, and is particularly concentrated in the region of the Golgi complex. Highest expression is found in brain, with lower levels detected in lung and liver.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: EH domain binding protein epsin 2; EH domain-binding protein; EPS-15-interacting protein 2; Eps15 binding protein; Epsin-2; Ibp2; Intersectin-EH-binding protein 2; unnamed protein product

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          Gene Aliases: 9530051D10Rik; AA536924; EHB21; EPN2; Ibp2; KIAA1065

          View more View less

          UniProt ID: (Human) O95208, (Mouse) Q8CHU3

          View more View less

          Entrez Gene ID: (Human) 22905, (Mouse) 13855, (Rat) 60443

          View more View less

          Function(s)
          protein binding phospholipid binding lipid binding clathrin binding cadherin binding
          Process(es)
          in utero embryonic development endocytosis Notch signaling pathway regulation of endocytosis embryonic organ development negative regulation of vascular endothelial growth factor receptor signaling pathway positive regulation of Notch signaling pathway negative regulation of sprouting angiogenesis
          It has to be done as per old AB suggested Products section.

          Disclaimer

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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