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Invitrogen
Erbin Polyclonal Antibody
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Product Details
PA5-149414
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Sheep
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived recombinant human Erbin, Lys496-Thr687
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with trehalose
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Densin-180-like protein; epididymis secretory protein Li 78; Erbb2-interacting protein; Erbin; Protein LAP2
Gene Aliases: ERBB2IP; ERBIN; HEL-S-78; KIAA1225; LAP2
UniProt ID: (Human) Q9NR18
Entrez Gene ID: (Human) 55914
protein targeting
cell cycle
cell adhesion
signal transduction
epidermal growth factor receptor signaling pathway
integrin-mediated signaling pathway
cell growth
negative regulation of NF-kappaB transcription factor activity
response to muramyl dipeptide
response to lipopolysaccharide
ERBB2 signaling pathway
intermediate filament cytoskeleton organization
basal protein localization
establishment or maintenance of epithelial cell apical/basal polarity
negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
cellular response to tumor necrosis factor
negative regulation of monocyte chemotactic protein-1 production
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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