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|Tested species reactivity||Human, Mouse, Non-human primate, Sheep, Rat|
|Published species reactivity||Rat, Pig, Non-human primate, Sheep, Bovine, Hamster, Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues A(55) E P Q K S P W C E A R S L E H(70) of rat ER beta.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 1mg/ml BSA|
|Contains||0.05% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Gel Shift (GS)||1-5 µl|
|Immunocytochemistry (ICC)||2-4 µg/ml|
|Immunofluorescence (IF)||0.5 µg/ml|
|Immunohistochemistry (Frozen) (IHC (F))||1-2 µg/mL|
|Immunohistochemistry (Paraffin) (IHC (P))||1-2 µg/mL|
|Western Blot (WB)||1-2 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 25 publications below|
|Gel Shift (GS)||See 1 publications below|
|Immunohistochemistry (IHC)||See 28 publications below|
|Immunocytochemistry (ICC)||See 7 publications below|
|ChIP assay (ChIP)||See 1 publications below|
|Immunoprecipitation (IP)||See 1 publications below|
|Flow Cytometry (Flow)||See 1 publications below|
PA1-311 detects estrogen receptor (ER) beta from human, non-human primate, mouse, ovine and rat tissues.
PA1-311 has been successfully used in Western blot, immunohistochemistry, immunocytochemistry and gel shift procedures. By Western blot, this antibody detects an ~55-62 kDa protein representing ER beta from rat brain homogenate. Immunohistochemical staining of ER beta in rat cerebellum with PA1-311 results in cytoplasmic staining in Purkinje neurons. PA1-311 efficiently supershifts rat ER beta/ER response element (vitellogenin xenopus A2 gene).
The PA1-311 immunogen is a synthetic peptide corresponding to residues A(55) E P Q K S P W C E A R S L E H(70) of rat ER beta.
Recombinant ER beta expressed in baculovirus system (Cat. # RP-311 and RP-312) can be purchased for control experiments in Western blot and gel shift assays.
The human ER-beta is a newly discovered estrogen receptor initially cloned and characterized from testis. The size and structure of ER-beta is very similar to ER-alpha with the ligand and DNA binding domains being highly conserved, while the amino terminus which serves as their transactivation domain has diverged significantly. Similar in function to ER-alpha ER-beta binds to estrogen with a high affinity and regulates estrogen specific gene activation through direct interaction with estrogen response elements (ERE's).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Both estrogen receptor α and β stimulate pituitary GH gene expression.
PA1-311 was used in western blot to test if estradiol affects GH synthesis in somatotrophs
|Avtanski D,Novaira HJ,Wu S,Romero CJ,Kineman R,Luque RM,Wondisford F,Radovick S||Molecular endocrinology (Baltimore, Md.) (28:40)||2014|
Estrogen receptor alpha and beta are both involved in the cerebral VEGF/Akt/NO pathway and cerebral angiogenesis in female mice.
PA1-311 was used in western blot to investigate the involvement of estrogen receptor alpha and beta in cerebral vascular endothelial growth factor /Akt/NO pathway and angiogenesis
|Jesmin S,Mowa CN,Sultana SN,Mia S,Islam R,Zaedi S,Sakuma I,Hattori Y,Hiroe M,Yamaguchi N||Biomedical research (Tokyo, Japan) (31:337)||2010|
VEGF signaling is disrupted in the hearts of mice lacking estrogen receptor alpha.
PA1-311 was used in western blot to investigate the mechanism for the cardioprotective effect of estrogen in women
|Jesmin S,Mowa CN,Sultana SN,Shimojo N,Togashi H,Iwashima Y,Kato N,Sato A,Sakuma I,Hiroe M,Hattori Y,Yamaguchi N,Kobayashi H||European journal of pharmacology (641:168)||2010|
Activation of transgenic estrogen receptor-beta by selected phytoestrogens in a stably transduced rat serotonergic cell line.
PA1-311 was used in western blot to investigate the estrogenic properties of isoflavones and naringenin-type flavanones
|Amer DA,Kretzschmar G,Müller N,Stanke N,Lindemann D,Vollmer G||The Journal of steroid biochemistry and molecular biology (120:208)||2010|
Down-regulation of endothelial cell estrogen receptor expression by the inflammation promoter LPS.
PA1-311 was used in western blot to investigate the effect of lipopolysaccharide on the endothelial cell estrogen receptor expression
|Holm A,Andersson KE,Nordström I,Hellstrand P,Nilsson BO||Molecular and cellular endocrinology (319:8)||2010|
Transient estradiol exposure during middle age in ovariectomized rats exerts lasting effects on cognitive function and the hippocampus.
PA1-311 was used in western blot to investigate the effect of transient estradiol exposeure on the cognition and brain function of ovariectomized rats
|Rodgers SP,Bohacek J,Daniel JM||Endocrinology (151:1194)||2010|
Differential effects of steroids on the synthesis of polyunsaturated fatty acids by human neuroblastoma cells.
PA1-311 was used in western blot to investigate the effects of steroids on polyunsaturated fatty acid synthesis by human neuroblastoma cells
|Extier A,Perruchot MH,Baudry C,Guesnet P,Lavialle M,Alessandri JM||Neurochemistry international (55:295)||2009|
Blockade of estrogen action upregulates estrogen receptor-alpha mRNA in the fetal brain.
PA1-311 was used in western blot to investigate the possible effect of circulating estrogens on the expression of estrogen receptors in the late-gestation sheep fetus
|Schaub CE,Wood CE||Neonatology (96:115)||2009|
Activity and intracellular location of estrogen receptors alpha and beta in human bronchial epithelial cells.
PA1-311 was used in western blot to estimate ERbeta protein expression level in human bronchial epithelial cells
|Ivanova MM,Mazhawidza W,Dougherty SM,Minna JD,Klinge CM||Molecular and cellular endocrinology (305:12)||2009|
The APOE4 genotype alters the response of microglia and macrophages to 17beta-estradiol.
PA1-311 was used in western blot to investigate the role of APOE4 genotype on the response of microglia and macrophages to 17beta-estradiol
|Brown CM,Choi E,Xu Q,Vitek MP,Colton CA||Neurobiology of aging (29:1783)||2008|
Resveratrol stimulates nitric oxide production by increasing estrogen receptor alpha-Src-caveolin-1 interaction and phosphorylation in human umbilical vein endothelial cells.
PA1-311 was used in western blot to investigate the mechanism for the stimulation of nitric oxide production by Resveratrol in human umbilical vein endothelial cells
|Klinge CM,Wickramasinghe NS,Ivanova MM,Dougherty SM||FASEB journal : official publication of the Federation of American Societies for Experimental Biology (22:2185)||2008|
Cerebral hypoperfusion increases estrogen receptor abundance in the ovine fetal brain and pituitary.
PA1-311 was used in western blot to show that the expression of ER in the brain and pituitary of fetal sheep areis influenced by circulating estrogen concentrations and acutely regulated in response to cerebral hypoperfusion
|Wood CE||Neuroendocrinology (87:216)||2008|
Estradiol stimulates transcription of nuclear respiratory factor-1 and increases mitochondrial biogenesis.
PA1-311 was used in western blot to study the transcriptional regulation of nuclear respiratory factor-1 by estradiol.
|Mattingly KA,Ivanova MM,Riggs KA,Wickramasinghe NS,Barch MJ,Klinge CM||Molecular endocrinology (Baltimore, Md.) (22:609)||2008|
Expressions of estrogen receptors in the bovine corpus luteum: cyclic changes and effects of prostaglandin F2alpha and cytokines.
PA1-311 was used in western blot to investigate the possible mechanisms for regulating different distinct estrogen functions by ER alpha and ER beta
|Shibaya M,Matsuda A,Hojo T,Acosta TJ,Okuda K||The Journal of reproduction and development (53:1059)||2007|
Androgens' effects to enhance learning may be mediated in part through actions at estrogen receptor-beta in the hippocampus.
PA1-311 was used in western blot to investigate the enhancing effect of testosterone on cognitive performance and its mechanism
|Edinger KL,Frye CA||Neurobiology of learning and memory (87:78)||2007|
Genistein modulates prostate epithelial cell proliferation via estrogen- and extracellular signal-regulated kinase-dependent pathways.
PA1-311 was used in western blot to investigate the effect of genistein on RWPE-1 cell proliferation and signal transduction and its mechanism
|Wang X,Clubbs EA,Bomser JA||The Journal of nutritional biochemistry (17:204)||2006|
Novel estrogen receptor coactivator PELP1/MNAR gene and ERbeta expression in salivary duct adenocarcinoma: potential therapeutic targets.
PA1-311 was used in western blot to study the expression and therapeutic potential of PELP1/MNAR and estrogen receptor-beta in salivary duct adenocarcinoma
|Vadlamudi RK,Balasenthil S,Sahin AA,Kies M,Weber RS,Kumar R,El-Naggar AK||Human pathology (36:670)||2005|
Somatic mutation of p53 leads to estrogen receptor alpha-positive and -negative mouse mammary tumors with high frequency of metastasis.
PA1-311 was used in western blot to investigate the role of somatic mutations of p53 in the estrogen receptor alpha-positive and -negative mouse mammary tumors.
|Lin SC,Lee KF,Nikitin AY,Hilsenbeck SG,Cardiff RD,Li A,Kang KW,Frank SA,Lee WH,Lee EY||Cancer research (64:3525)||2004|
|Non-human primate||Not Cited||
Relaxin regulation of endometrial structure and function in the rhesus monkey.
PA1-311 was used in western blot to investigate the role of the relaxin in regulating endometrial structure and function.
|Goldsmith LT,Weiss G,Palejwala S,Plant TM,Wojtczuk A,Lambert WC,Ammur N,Heller D,Skurnick JH,Edwards D,Cole DM||Proceedings of the National Academy of Sciences of the United States of America (101:4685)||2004|
Increased expression of estrogen receptor beta in pachytene spermatocytes after short-term methoxyacetic acid administration.
PA1-311 was used in western blot to study the possible changes of normal ER beta levels during the massive and stage-specific cellular apoptosis
|Tirado OM,Selva DM,Toràn N,Suárez-Quian CA,Jansen M,McDonnell DP,Reventós J,Munell F||Journal of andrology (25:84)||2003|
Identification of estrogen receptor beta expression in Chinese hamster ovary (CHO) cells and comparison of estrogen-responsive gene transcription in cells adapted to serum-free media.
PA1-311 was used in western blot to study estrogen receptor beta expression in Chinese hamster ovary cells
|Thomas PB,Risinger KE,Klinge CM||The Journal of steroid biochemistry and molecular biology (86:41)||2003|
Expression and localisation of oestrogen and progesterone receptors in the bovine mammary gland during development, function and involution.
PA1-311 was used in western blot to investigate the developmental role of oestrogen and progesterone receptors in bovine mammary glands
|Schams D,Kohlenberg S,Amselgruber W,Berisha B,Pfaffl MW,Sinowatz F||The Journal of endocrinology (177:305)||2003|
Expression of estrogen receptor alpha and beta in myometrium of premenopausal and postmenopausal women.
PA1-311 was used in western blot to study the expression in pre- and post-menopausal myometrium of estrogen receptor-alpha and estrogen receptor-beta
|Sakaguchi H,Fujimoto J,Aoki I,Tamaya T||Steroids (68:11)||2003|
The agonist activity of tamoxifen is inhibited by the short heterodimer partner orphan nuclear receptor in human endometrial cancer cells.
PA1-311 was used in western blot to investigate the role of the short heterodimer partner orphan nuclear receptor in regulating the agonist activity of tamoxifen.
|Klinge CM,Jernigan SC,Risinger KE||Endocrinology (143:853)||2002|
|Non-human primate||Not Cited||
Expression of estrogen receptor alpha and beta in the rhesus monkey corpus luteum during the menstrual cycle: regulation by luteinizing hormone and progesterone.
PA1-311 was used in western blot to detect the expression and level of estrogen receptor beta in the monkey corpus luteum
|Duffy DM,Chaffin CL,Stouffer RL||Endocrinology (141:1711)||2000|
Characterization of estrogen response element binding proteins as biomarkers of breast cancer behavior.
PA1-311 was used in EMSA to study the prognostic value of estrogen resonse element binding proteins in breast cancer
|Kruer TL,Cummins TD,Powell DW,Wittliff JL||Clinical biochemistry (46:1739)||2013|
Effect of raloxifene and atorvastatin in atherosclerotic process in ovariectomized rats.
PA1-311 was used in immunohistochemistry to study the potential therapeutic effect of combined raloxifene and atorvastatin in atherosclerosis in aged ovariectomized rats
|Cetinkaya Demir B,Uyar Y,Ozbilgin K,Köse C||The journal of obstetrics and gynaecology research (39:229)||2013|
Estrogen regulates DNA synthesis in human gingival epithelial cells displaying strong estrogen receptor β immunoreactivity.
PA1-311 was used in immunohistochemistry to investigate the effect of estrogen on the proliferation of gingival epithelial cells
|Nebel D,Bratthall G,Ekblad E,Norderyd O,Nilsson BO||Journal of periodontal research (46:622)||2011|
Activation of mutated K-ras in donor endometrial epithelium and stroma promotes lesion growth in an intact immunocompetent murine model of endometriosis.
PA1-311 was used in immunohistochemistry to develop and evaluate a murine model of endometriosis
|Cheng CW,Licence D,Cook E,Luo F,Arends MJ,Smith SK,Print CG,Charnock-Jones DS||The Journal of pathology (224:261)||2011|
C-28/I2 and T/C-28a2 chondrocytes as well as human primary articular chondrocytes express sex hormone and insulin receptors--Useful cells in study of cartilage metabolism.
PA1-311 was used in immunohistochemistry to investigate the expression of sex hormone and insulin receptors in chondrocytes and human primary articular cartilage cells
|Claassen H,Schicht M,Brandt J,Reuse K,Schädlich R,Goldring MB,Guddat SS,Thate A,Paulsen F||Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft (193:23)||2011|
Assessment of estrogen receptors and apoptotic factors in cryopreserved human ovarian cortex.
PA1-311 was used in immunohistochemistry to investigate the expression of estrogen receptors and apoptotic factors in human ovarian tissues before and after cryopreservation
|Depalo R,Lorusso F,Bettocchi S,Selvaggi L,Cavallini A,Valentini AM,Caruso ML,Lippolis C||Systems biology in reproductive medicine (55:236)||2009|
Estradiol improves cerebellar memory formation by activating estrogen receptor beta.
PA1-311 was used in immunohistochemistry to study the effect of estradiol in cerebellar memory formation.
|Andreescu CE,Milojkovic BA,Haasdijk ED,Kramer P,De Jong FH,Krust A,De Zeeuw CI,De Jeu MT||The Journal of neuroscience : the official journal of the Society for Neuroscience (27:10832)||2007|
Flaxseed alone or in combination with tamoxifen inhibits MCF-7 breast tumor growth in ovariectomized athymic mice with high circulating levels of estrogen.
PA1-311 was used in immunohistochemistry to evaluate the effect of flaxseed alone and tamoxifen on MCF-7 breast tumor growth
|Chen J,Power KA,Mann J,Cheng A,Thompson LU||Experimental biology and medicine (Maywood, N.J.) (232:1071)||2007|
Dietary flaxseed interaction with tamoxifen induced tumor regression in athymic mice with MCF-7 xenografts by downregulating the expression of estrogen related gene products and signal transduction pathways.
PA1-311 was used in immunohistochemistry to investigate the anti-tumor therapeutic efficacy of dietary flaxseed with tamoxifen in athymic mice with MCF-7 Xenografts
|Chen J,Power KA,Mann J,Cheng A,Thompson LU||Nutrition and cancer (58:162)||2007|
Immunohistochemical localization of estrogen receptors ERalpha and ERbeta in the spiny mouse (Acomys cahirinus) ovary during postnatal development.
PA1-311 was used in immunohistochemistry to investigate the distribution of estrogen receptors alpha and beta in spiny mouse ovary
|Hułas-Stasiak M,Gawron A||Journal of molecular histology (38:25)||2007|
Estrogen receptors in the uterus and ovarian follicles of gilts treated with dihydrotestosterone.
PA1-311 was used in immunohistochemistry to investigate the expression of estrogen receptor alpha and beta in the uterus and ovarian follicles
|Cárdenas H,Pope WF||Domestic animal endocrinology (29:523)||2005|
Estrogen receptor alpha and beta immunoreactive neurons in normal adult and aged female rat hippocampus: a qualitative and quantitative study.
PA1-311 was used in immunohistochemistry to investigate the expression of estrogen in the rat hippocampus
|Mehra RD,Sharma K,Nyakas C,Vij U||Brain research (1056:22)||2005|
Chromosomal mapping and quantitative analysis of estrogen-related receptor alpha-1, estrogen receptors alpha and beta and progesterone receptor in the bovine mammary gland.
PA1-311 was used in immunohistochemistry to study the changes of the expression of ER alpha, ER beta, PR and ERR alpha throughout development and in different functional states of the bovine mammary gland and to identify corresponding sites in the bo
|Connor EE,Wood DL,Sonstegard TS,da Mota AF,Bennett GL,Williams JL,Capuco AV||The Journal of endocrinology (185:593)||2005|
Upregulation of myocardial estrogen receptors in human aortic stenosis.
PA1-311 was used in immunohistochemistry to demonstrate that ER-alpha and -beta are upregulated by myocardial pressure load in human aortic stenosis
|Nordmeyer J,Eder S,Mahmoodzadeh S,Martus P,Fielitz J,Bass J,Bethke N,Zurbrügg HR,Pregla R,Hetzer R,Regitz-Zagrosek V||Circulation (110:3270)||2004|
Estrogen receptor beta expression and apoptosis of spermatocytes of mice overexpressing a rat androgen-binding protein transgene.
PA1-311 was used in immunohistochemistry to investigate the possible relationship of overexpression of ABP in the testis with the expression change of ER beta in pachytene spermatocytes that arrest at meiosis and degenerate by apoptosis
|Selva DM,Tirado OM,Toràn N,Suárez-Quian CA,Reventos J,Munell F||Biology of reproduction (71:1461)||2004|
Expression of estrogen receptor-beta in the postischemic monkey hippocampus.
PA1-311 was used in immunohistochemistry to investigate the level of estrogen receptor beta in monkey hippocampus
|Takahashi N,Tonchev AB,Koike K,Murakami K,Yamada K,Yamashima T,Inoue M||Neuroscience letters (369:9)||2004|
Expression of the insulin-like growth factor-I receptor in primary breast cancer and lymph node metastases: correlations with estrogen receptors alpha and beta.
PA1-311 was used in immunohistochemistry to investigate the expression of insulin-like growth factor-I receptor in breast cancer
|Koda M,Sulkowski S,Garofalo C,Kanczuga-Koda L,Sulkowska M,Surmacz E||Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et me¿tabolisme (35:794)||2004|
Para/autocrine regulation of estrogen receptors in hippocampal neurons.
PA1-311 was used in immunohistochemistry to investigate the regulation of estrogen receptor by the para/autocrine process in hippocampal neurons
|Prange-Kiel J,Wehrenberg U,Jarry H,Rune GM||Hippocampus (13:226)||2003|
Exposure to the environmental estrogen bisphenol A differentially modulated estrogen receptor-alpha and -beta immunoreactivity and mRNA in male mouse testis.
PA1-311 was used in immunohistochemistry to investigate the influence of bisphenol A on estrogen receptor alpha/beta expression in male mouse testis
|Takao T,Nanamiya W,Nazarloo HP,Matsumoto R,Asaba K,Hashimoto K||Life sciences (72:1159)||2003|
Immunolocalization of estrogen receptor alpha and beta in gastric epithelium and enteric neurons.
PA1-311 was used in immunohistochemistry to study the mechanism for the dimorphism in gastric acid secretion between sexes
|Campbell-Thompson M,Reyher KK,Wilkinson LB||The Journal of endocrinology (171:65)||2001|
Estrogen receptors alpha and beta are differentially expressed in developing human bone.
PA1-311 was used in immunohistochemistry to study the expression of estrogen receptors alpha and beta in developing human bone.
|Bord S,Horner A,Beavan S,Compston J||The Journal of clinical endocrinology and metabolism (86:2309)||2001|
Dominant expression and distribution of oestrogen receptor beta over oestrogen receptor alpha in the human corpus luteum.
PA1-311 was used in immunohistochemistry to investigate the role of estrogen receptor beta
|Hosokawa K,Ottander U,Wahlberg P,Ny T,Cajander S,Olofsson IJ||Molecular human reproduction (7:137)||2001|
Expression of estrogen receptor-beta protein and mRNA in the cerebellum of the rat.
PA1-311 was used in immunohistochemistry to determine the estrogen receptor beta protein expression in the rat cerebellum
|Price RH,Handa RJ||Neuroscience letters (288:115)||2000|
Differential distribution of ERalpha and ERbeta mRNA in intrauterine tissues of the pregnant rhesus monkey.
PA1-311 was used in immunohistochemistry to demonstrate the differential distribution of ERalpha and ERbeta mRNA in intrauterine tissues of the pregnant rhesus monkey
|Wu WX,Ma XH,Smith GC,Nathanielsz PW||American journal of physiology. Cell physiology (278:C190)||2000|
Estrogen receptor-dependent regulation of sensory neuron survival in developing dorsal root ganglion.
PA1-311 was used in immunohistochemistry to study the role of estrogen and estrogen receptors in the development and survival of DRG neurons.
|Patrone C,Andersson S,Korhonen L,Lindholm D||Proceedings of the National Academy of Sciences of the United States of America (96:10905)||1999|
Differentiation between vasculoprotective and uterotrophic effects of ligands with different binding affinities to estrogen receptors alpha and beta.
PA1-311 was used in immunohistochemistry to study the vasculoprotective and uterotrophic mechanisms of estrogen receptors alpha and beta.
|Mäkelä S,Savolainen H,Aavik E,Myllärniemi M,Strauss L,Taskinen E,Gustafsson JA,Häyry P||Proceedings of the National Academy of Sciences of the United States of America (96:7077)||1999|
Expression of the vitamin D receptor, of estrogen and thyroid hormone receptor alpha- and beta-isoforms, and of the androgen receptor in cultures of native mouse bone marrow and of stromal/osteoblastic cells.
PA1-311 was used in immunohistochemistry to investigate the expression of steroid/thyroid hormone receptors in native mouse bone marrow cell culture and stromal/osteoblastic cells
|Gruber R,Czerwenka K,Wolf F,Ho GM,Willheim M,Peterlik M||Bone (24:465)||1999|
Cloning, sequencing, and localization of bovine estrogen receptor-beta within the ovarian follicle.
PA1-311 was used in immunohistochemistry to investigate the role of bovine estrogen receptor-beta in ovarian follicular growth and maturation
|Rosenfeld CS,Yuan X,Manikkam M,Calder MD,Garverick HA,Lubahn DB||Biology of reproduction (60:691)||1999|
Differential colocalization of estrogen receptor beta (ERbeta) with oxytocin and vasopressin in the paraventricular and supraoptic nuclei of the female rat brain: an immunocytochemical study.
PA1-311 was used in immunohistochemistry to study the role of the estrogen during the modulation of the oxytocin and arginine-vasopressin systems
|Alves SE,Lopez V,McEwen BS,Weiland NG||Proceedings of the National Academy of Sciences of the United States of America (95:3281)||1998|
The GPER1 agonist G-1 attenuates endothelial cell proliferation by inhibiting DNA synthesis and accumulating cells in the S and G2 phases of the cell cycle.
PA1-311 was used in immunocytochemistry to investigate the effect of the GPER1 agonist G-1 on endothelial cell proliferation
|Holm A,Baldetorp B,Olde B,Leeb-Lundberg LM,Nilsson BO||Journal of vascular research (48:327)||2011|
Contraceptive steroids from pharmaceutical waste perturbate junctional communication in Sertoli cells.
PA1-311 was used in immunocytochemistry to study the effect of contraceptive steroids on Sertoli cell junctions
|Tramoni M,Gilleron J,Tahiri K,Carette D,Corvol MT,Segretain D,Pointis G,Savouret JF||Biochimie (91:1366)||2009|
Difficulties in recognizing families with Hereditary Non-polyposis Colorectal Carcinoma. Presentation of 4 families with proven mutation.
PA1-311 was used in immunocytochemistry to conduct the genetic analysis of hereditary non-polyposis colorectal carcinoma
|Tanyi M,Olasz J,Kámory E,Csuka O,Tanyi JL,Ress Z,Damjanovich L||European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology (34:1322)||2008|
Role of wild-type estrogen receptor-beta in mitochondrial cytoprotection of cultured normal male and female human lens epithelial cells.
PA1-311 was used in immunocytochemistry to show the localization of ERbeta in human normal lens epithelium
|Flynn JM,Dimitrijevich SD,Younes M,Skliris G,Murphy LC,Cammarata PR||American journal of physiology. Endocrinology and metabolism (295:E637)||2008|
Stimulation of oestrogen receptor-expressing endothelial cells with oestrogen reduces proliferation of cocultured vascular smooth muscle cells.
PA1-311 was used in immunocytochemistry to study the effects of estrogen on the growth of endothelial cells and cocultured vascular smooth muscle cells
|Odenlund M,Ekblad E,Nilsson BO||Clinical and experimental pharmacology & physiology (35:245)||2008|
Nongenomic, endothelium-independent effects of estrogen on human coronary smooth muscle are mediated by type I (neuronal) NOS and PI3-kinase-Akt signaling.
PA1-311 was used in immunocytochemistry to study how nongenomic estrogen signal is transduced in human coronary artery smooth muscle cells
|Han G,Ma H,Chintala R,Miyake K,Fulton DJ,Barman SA,White RE||American journal of physiology. Heart and circulatory physiology (293:H314)||2007|
Expression and localization of estrogen receptor-beta in annulus cells of the human intervertebral disc and the mitogenic effect of 17-beta-estradiol in vitro.
PA1-311 was used in immunocytochemistry to study the role of ER in human intervertebral disc cells and the effects on disc cell proliferation.
|Gruber HE,Yamaguchi D,Ingram J,Leslie K,Huang W,Miller TA,Hanley EN||BMC musculoskeletal disorders (3:null)||2003|
Genome-wide dynamics of chromatin binding of estrogen receptors alpha and beta: mutual restriction and competitive site selection.
PA1-311 was used in chimmunoprecipitation to investigate the interplay between estrogen receptor alpha and estrogen receptor beta at the genomic level
|Charn TH,Liu ET,Chang EC,Lee YK,Katzenellenbogen JA,Katzenellenbogen BS||Molecular endocrinology (Baltimore, Md.) (24:47)||2010|
Estrogen Receptors alpha and beta as determinants of gene expression: influence of ligand, dose, and chromatin binding.
PA1-311 was used in immunoprecipitation to investigate the mechanism of gene expression regulation by estrogen receptor alpha and beta
|Chang EC,Charn TH,Park SH,Helferich WG,Komm B,Katzenellenbogen JA,Katzenellenbogen BS||Molecular endocrinology (Baltimore, Md.) (22:1032)||2008|
Expression of the estrogen receptor in blood neutrophils of dairy cows during the periparturient period.
PA1-311 was used in flow cytometry to investigate the estrogen receptor protein expression level in neutrophils of cows in early lactation.
|Lamote I,Meyer E,De Ketelaere A,Duchateau L,Burvenich C||Theriogenology (65:1082)||2006|
ER Beta; ER-beta; ESR-Beta; ESR2; estrogen receptor 2 (ER beta); estrogen receptor 2 beta; Estrogen receptor beta; estrogen receptor beta 4; Nuclear receptor subfamily 3 group A member 2; oestrogen receptor beta; steroid receptor
ER-BETA; ER[b]; ERB; Erb2; ERBETA; ESR-BETA; ESR2; ESRB; ESTRB; NR3A2