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Proteintech
FA2H Polyclonal Antibody
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Product Details
15452-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FA2H Fusion Protein Ag7717 (1-164 aa encoded by BC002679)
Conjugate
Form
Liquid
Concentration
0.28 mg/mL
Amount
42 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAPAPPPAA SFSPSEVQRR LAAGACWVRR GARLYDLSSF VRHHPGGEQL LRARAGQDIS ADLDGPPHRH SANARRWLEQ YYVGELRGEQ QGSMENEPVA LEETQKTDPA MEPRFKVVDW DKDLVDWRKP LLWQVGHLGE KYDEWVHQPV TRPIRLFHSD LIEGL (1-164 aa encoded by BC002679)
Target Information
FA2H is a protein that catalyzes the synthesis of 2-hydroxysphingolipids, a subset of sphingolipids that contain 2-hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structural diversity arises from modification of the hydrophobic ceramide moiety, such as by 2-hydroxylation of the N-acyl chain, and the existence of many different head groups.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Fatty acid 2-hydroxylase; Fatty acid alpha-hydroxylase; fatty acid hydroxylase domain containing 1; Fatty acid hydroxylase domain-containing protein 1; FLJ25287; spastic paraplegia 35 (autosomal recessive); unnamed protein product; WD repeat domain 59
Gene Aliases: FA2H; FAAH; FAH1; FAXDC1; G630055L08Rik; RGD1310347; SCS7; SPG35; Wdr59
UniProt ID: (Human) Q7L5A8, (Rat) Q2LAM0, (Mouse) Q5MPP0
Entrez Gene ID: (Human) 79152, (Rat) 307855, (Mouse) 338521
iron ion binding
protein binding
oxidoreductase activity
heme binding
metal ion binding
fatty acid alpha-hydroxylase activity
free fatty acid 2-hydroxylase activity
4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase activity
N-ethylmaleimide reductase activity
reduced coenzyme F420 dehydrogenase activity
sulfur oxygenase reductase activity
malolactic enzyme activity
NADPH:sulfur oxidoreductase activity
epoxyqueuosine reductase activity
hydroxylase
sebaceous gland cell differentiation
lipid metabolic process
fatty acid metabolic process
fatty acid biosynthetic process
sphingolipid metabolic process
glucosylceramide biosynthetic process
galactosylceramide biosynthetic process
lipid biosynthetic process
sphingolipid biosynthetic process
lipid modification
central nervous system myelin maintenance
peripheral nervous system myelin maintenance
regulation of hair cycle
plasma membrane raft organization
ceramide biosynthetic process
establishment of skin barrier
regulation of sebum secreting cell proliferation
regulation of acinar cell proliferation
regulation of cell proliferation
oxidation-reduction process
transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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