This antibody is predicted to react with non-human primate and rat based on sequence homology.
FA2H is a protein that catalyzes the synthesis of 2-hydroxysphingolipids, a subset of sphingolipids that contain 2-hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structural diversity arises from modification of the hydrophobic ceramide moiety, such as by 2-hydroxylation of the N-acyl chain, and the existence of many different head groups.
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Protein Aliases: Fatty acid 2-hydroxylase; Fatty acid alpha-hydroxylase; fatty acid hydroxylase domain containing 1; FLJ25287; spastic paraplegia 35 (autosomal recessive)
Gene Aliases: FA2H; FAAH; FAH1; FAXDC1; G630055L08Rik; SCS7; SPG35