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FABP4 Polyclonal Antibody

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Antibody Testing Data (11)

FABP4 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 11

FABP4 Antibody (15872-1-AP) in ICC/IF

Immunofluorescent analysis of HUVEC cells using 15872-1-AP (FABP4 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).

FABP4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FABP4 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))

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Product Details

15872-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 6 publications 6 publications

Immunohistochemistry (IHC)

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunohistochemistry (PFA fixed) (IHC (PFA))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:20-1:200

View 3 publications 3 publications

Miscellaneous PubMed (Misc)

View 1 publication 1 publication

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

FABP4 Fusion Protein Ag8631 (6-132 aa encoded by BC003672)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.27 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: VGTWKLVSS ENFDDYMKEV GVGFATRKVA GMAKPNMIIS VNGDVITIKS ESTFKNTEIS FILGQEFDEV TADDRKVKST ITLDGGVLVH VQKWDGKSTT IKRKREDDKL VVECVMKGVT STRVYERA (6-132 aa encoded by BC003672)

Target Information

FABP4 belongs to the fatty acid binding protein (FABP) family. FABPs contribute to the transport of fatty acids and other lipids in various cellular pathways. FABP4 is expressed in adipocytes, macrophages, monocyte-derived dendritic cells, and myoepithelial cells. It delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Autophagy loss impedes cancer-associated fibroblast activation via downregulating proline biosynthesis.

Autophagy

Bai J,Liu T,Tu B,Yuan M,Shu Z,Fan M,Huo S,Guo Y,Wang L,Wang H,Zhao Y

Wed Feb 01 00:00:00 EST 2023

Autophagy loss impedes cancer-associated fibroblast activation via downregulating proline biosynthesis.

Autophagy

Bai J,Liu T,Tu B,Yuan M,Shu Z,Fan M,Huo S,Guo Y,Wang L,Wang H,Zhao Y

Wed Feb 01 00:00:00 EST 2023

Dynamic interplay between IL-1 and WNT pathways in regulating dermal adipocyte lineage cells during skin development and wound regeneration.

Cell reports

Sun L,Zhang X,Wu S,Liu Y,Guerrero-Juarez CF,Liu W,Huang J,Yao Q,Yin M,Li J,Ramos R,Liao Y,Wu R,Xia T,Zhang X,Yang Y,Li F,Heng S,Zhang W,Yang M,Tzeng CM,Ji C,Plikus MV,Gallo RL,Zhang LJ

Tue Jun 27 00:00:00 EDT 2023

Inflammatory Microenvironment Accelerates Bone Marrow Mesenchymal Stem Cell Aging.

Frontiers in bioengineering and biotechnology

Peng X,Zhou X,Yin Y,Luo B,Liu Y,Yang C

Sat Jul 16 00:00:00 EDT 2022

Supplementation of Probiotic Butyricicoccus pullicaecorum Mediates Anticancer Effect on Bladder Urothelial Cells by Regulating Butyrate-Responsive Molecular Signatures.

Diagnostics (Basel, Switzerland)

Wang YC,Ku WC,Liu CY,Cheng YC,Chien CC,Chang KW,Huang CJ

Sat Dec 04 00:00:00 EST 2021

Single-cell mapping reveals new markers and functions of lymphatic endothelial cells in lymph nodes.

PLoS biology

Fujimoto N,He Y,D'Addio M,Tacconi C,Detmar M,Dieterich LC

Wed Apr 01 00:00:00 EDT 2020

Deregulating the CYP2C19/Epoxy-Eicosatrienoic Acid-Associated FABP4/FABP5 Signaling Network as a Therapeutic Approach for Metastatic Triple-Negative Breast Cancer.

Cancers

Apaya MK,Hsiao PW,Yang YC,Shyur LF

Mon Jan 13 00:00:00 EST 2020

Deregulating the CYP2C19/Epoxy-Eicosatrienoic Acid-Associated FABP4/FABP5 Signaling Network as a Therapeutic Approach for Metastatic Triple-Negative Breast Cancer.

Cancers

Apaya MK,Hsiao PW,Yang YC,Shyur LF

Mon Jan 13 00:00:00 EST 2020

Deregulating the CYP2C19/Epoxy-Eicosatrienoic Acid-Associated FABP4/FABP5 Signaling Network as a Therapeutic Approach for Metastatic Triple-Negative Breast Cancer.

Cancers

Apaya MK,Hsiao PW,Yang YC,Shyur LF

Mon Jan 13 00:00:00 EST 2020

Deregulating the CYP2C19/Epoxy-Eicosatrienoic Acid-Associated FABP4/FABP5 Signaling Network as a Therapeutic Approach for Metastatic Triple-Negative Breast Cancer.

Cancers

Apaya MK,Hsiao PW,Yang YC,Shyur LF

Mon Jan 13 00:00:00 EST 2020

Dlgap1 negatively regulates browning of white fat cells through effects on cell proliferation and apoptosis.

Lipids in health and disease

Zhang J,Yang J,Yang N,Ma J,Lu D,Dong Y,Liang H,Liu D,Cang M

Fri Mar 13 00:00:00 EDT 2020

Identity Noise and Adipogenic Traits Characterize Dermal Fibroblast Aging.

Cell

Salzer MC,Lafzi A,Berenguer-Llergo A,Youssif C,Castellanos A,Solanas G,Peixoto FO,Stephan-Otto Attolini C,Prats N,Aguilera M,Martín-Caballero J,Heyn H,Benitah SA

Thu Nov 29 00:00:00 EST 2018

Identity Noise and Adipogenic Traits Characterize Dermal Fibroblast Aging.

Cell

Salzer MC,Lafzi A,Berenguer-Llergo A,Youssif C,Castellanos A,Solanas G,Peixoto FO,Stephan-Otto Attolini C,Prats N,Aguilera M,Martín-Caballero J,Heyn H,Benitah SA

Thu Nov 29 00:00:00 EST 2018

Human adipocytes from the subcutaneous superficial layer have greater adipogenic potential and lower PPAR-γ DNA methylation levels than deep layer adipocytes.

American journal of physiology. Cell physiology

Kosaka K,Kubota Y,Adachi N,Akita S,Sasahara Y,Kira T,Kuroda M,Mitsukawa N,Bujo H,Satoh K

Mon Aug 01 00:00:00 EDT 2016

Human adipocytes from the subcutaneous superficial layer have greater adipogenic potential and lower PPAR-γ DNA methylation levels than deep layer adipocytes.

American journal of physiology. Cell physiology

Kosaka K,Kubota Y,Adachi N,Akita S,Sasahara Y,Kira T,Kuroda M,Mitsukawa N,Bujo H,Satoh K

Mon Aug 01 00:00:00 EDT 2016

miR-20a regulates adipocyte differentiation by targeting lysine-specific demethylase 6b and transforming growth factor-β signaling.

International journal of obesity (2005)

Zhou J,Guo F,Wang G,Wang J,Zheng F,Guan X,Chang A,Zhang X,Dai C,Li S,Li X,Wang B

Sat Aug 01 00:00:00 EDT 2015

miR-20a regulates adipocyte differentiation by targeting lysine-specific demethylase 6b and transforming growth factor-β signaling.

International journal of obesity (2005)

Zhou J,Guo F,Wang G,Wang J,Zheng F,Guan X,Chang A,Zhang X,Dai C,Li S,Li X,Wang B

Sat Aug 01 00:00:00 EDT 2015

Adipocyte fatty acid binding protein in atherosclerotic plaques is associated with local vulnerability and is predictive for the occurrence of adverse cardiovascular events.

European heart journal

Peeters W,de Kleijn DP,Vink A,van de Weg S,Schoneveld AH,Sze SK,van der Spek PJ,de Vries JP,Moll FL,Pasterkamp G

Fri Jul 01 00:00:00 EDT 2011

Adipocyte fatty acid binding protein in atherosclerotic plaques is associated with local vulnerability and is predictive for the occurrence of adverse cardiovascular events.

European heart journal

Peeters W,de Kleijn DP,Vink A,van de Weg S,Schoneveld AH,Sze SK,van der Spek PJ,de Vries JP,Moll FL,Pasterkamp G

Fri Jul 01 00:00:00 EDT 2011

Bioinformatics

Protein Aliases: 3T3-L1 lipid-binding protein; A-FABP; adipocyte fatty acid binding protein; Adipocyte lipid binding protein; Adipocyte lipid-binding protein; adipocyte protein aP2; Adipocyte-type fatty acid-binding protein; AFABP; ALBP; epididymis secretory protein Li 104; Fatty acid binding protein 4 adipocyte; fatty acid binding protein 4, adipocyte; Fatty acid-binding protein 4; Fatty acid-binding protein, adipocyte; HEL S 104; Myelin P2 protein homolog; P15; P2 adipocyte protein; Protein 422

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Gene Aliases: 422/aP2; A-FABP; AFABP; ALBP; ALBP/Ap2; Ap2; FABP4; HEL-S-104; Lbpl

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UniProt ID: (Human) P15090, (Mouse) P04117

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Entrez Gene ID: (Human) 2167, (Mouse) 11770, (Rat) 79451

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Function(s)

transporter activity fatty acid binding lipid binding protein binding

Process(es)

cytokine production negative regulation of protein kinase activity transport triglyceride catabolic process cholesterol homeostasis negative regulation of transcription, DNA-templated positive regulation of inflammatory response white fat cell differentiation brown fat cell differentiation cellular response to lithium ion fatty acid metabolic process positive regulation of cell proliferation response to drug response to glucocorticoid

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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FABP4 Polyclonal Antibody

FABP4 Antibody (15872-1-AP) in ICC/IF

Product Details

15872-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (PFA fixed) (IHC (PFA))

Immunocytochemistry (ICC/IF)

Miscellaneous PubMed (Misc)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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