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Invitrogen
FABP5 Polyclonal Antibody
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Product Details
PA5-79233
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human Fatty Acid Binding Protein 5 (2-16aa ATVQQLEGRWRLVDS).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: HELA whole cell, HEPG2 whole cell. IHC: Human Intestinal Cancer Tissue.
Target Information
FABP5 (fatty acid binding protein 5 (psoriasis-associated)) is a proteinthat in humans is encoded by theFABP5 gene, also known as PAFABP, EFABP, E-FABP, KFABP, PA-FABP, Epidermal-type fatty acid-binding protein, Fatty acid-binding protein 5, Psoriasis-associated fatty acid-binding protein homolog. It is a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. The PAFABP cDNA encodes a 135-amino acid protein with molecular weight 15,164. This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated inpsoriasistissue. It is though that FABPs roles include fatty acid uptake, transport, and metabolism. Kaczocha et al. (2009) identifiedFABP5and FABP7 as cytosolic proteins that transport AEA from the plasma membrane to subcellular fatty acid amide hydrolase, where it is hydrolyzed and inactivated. FABP3 did not show this specific transport function.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E-FABP; E-FABPPAFABP; Epidermal-type fatty acid-binding protein; fatty acid binding protein 5 (psoriasis-associated); Fatty acid-binding protein 5; Fatty acid-binding protein, epidermal; PA-FABP; PA-FABPepidermal; Psoriasis-associated fatty acid-binding protein homolog; unnamed protein product
Gene Aliases: E-FABP; EFABP; FABP5; KFABP; PA-FABP; PAFABP
UniProt ID: (Human) Q01469
Entrez Gene ID: (Human) 2171
glucose metabolic process
lipid metabolic process
phosphatidylcholine biosynthetic process
lipid transport
epidermis development
negative regulation of glucose transport
fatty acid transport
long-chain fatty acid transport
regulation of prostaglandin biosynthetic process
positive regulation of peroxisome proliferator activated receptor signaling pathway
glucose homeostasis
regulation of sensory perception of pain
retrograde trans-synaptic signaling by endocannabinoid
regulation of retrograde trans-synaptic signaling by endocanabinoid
positive regulation of cold-induced thermogenesis
lipid transport across blood brain barrier
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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