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Invitrogen
FADS1 Polyclonal Antibody
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FIGURE: 1 / 1
FADS1 Antibody (PA5-95735) in WB
Western blot analysis of FADS1 in extracts of various cell lines. Samples were incubated with FADS1 Polyclonal antibody (Product # PA5-95735) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
Product Details
PA5-95735
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human FADS1 (NP_0375343)
Conjugate
Form
Liquid
Concentration
1.14 mg/mL
Amount
114 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: YNISEFTRRH PGGSRVISHY AGQDATDPFV AFHINKGLVK KYMNSLLIGE LSPEQPSFEP TKNKELTDEF RELRATVERM GLMKANHVFF LLYLLHILLL D; Positive Samples: 293T, Mouse testis, Rat lung
Target Information
The protein encoded by this gene is a member of the fatty acid desaturase gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13. 1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acyl-CoA (8-3)-desaturase; BC269730_2; D5D; delta(5) desaturase; Delta(5) fatty acid desaturase; delta-5 desaturase; delta-5 fatty acid desaturase; Fatty acid desaturase 1; FLJ38956; FLJ90273; linoleoyl-CoA desaturase (delta-6-desaturase)-like 1; unnamed protein product
Gene Aliases: 0710001O03Rik; A930006B21Rik; AI317215; D5D; DSD; FADS1; FADS6; FADSD5; LLCDL1; TU12
UniProt ID: (Human) B2RAI0, (Mouse) Q920L1, (Rat) Q920R3
Entrez Gene ID: (Human) 3992, (Mouse) 76267, (Rat) 84575
C-5 sterol desaturase activity
linoleoyl-CoA desaturase activity
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
omega-6 fatty acid desaturase activity
acyl-CoA (8-3)-desaturase activity
acyl-CoA desaturase activity
iron ion binding
heme binding
lipid metabolic process
fatty acid metabolic process
fatty acid biosynthetic process
unsaturated fatty acid biosynthetic process
transport
cellular response to starvation
arachidonic acid metabolic process
long-chain fatty acid biosynthetic process
oxidation-reduction process
aging
response to nutrient
response to sucrose
response to organic substance
response to organic cyclic compound
response to insulin
response to vitamin A
response to isolation stress
regulation of transcription, DNA-templated
cell-cell signaling
phospholipid biosynthetic process
alpha-linolenic acid metabolic process
linoleic acid metabolic process
regulation of cell differentiation
icosanoid biosynthetic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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