Recommended positive controls: A431, H1299, HeLa, HepG2, Molt-4, NIH-3T3.
Predicted reactivity: Mouse (98%), Rat (98%), Zebrafish (87%), Xenopus laevis (91%), Rhesus Monkey (100%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Fas (TNFRSF6) associated factor 1; FAS-associated factor 1; hFAF1; TNFRSF6-associated factor 1; UBX domain protein 3A; UBX domain-containing protein 12; UBX domain-containing protein 3A
Gene Aliases: AA408698; CGI-03; Dffrx; FAF1; Fam; hFAF1; HFAF1s; UBXD12; UBXN3A