Proteintech

FAH Polyclonal Antibody

View all (11) FAH antibodies

Questions & Answers

Questions & Answers

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FAH Antibody in Western Blot (WB) — Mouse liver tissue were subjected to SDS PAGE followed by western blot with 14928-1-AP (FAH antibody) at dilution of 1:1200 incubated at room temperature for 1.5 hours.

FAH Antibody in Western Blot (WB) — Human liver tissue were subjected to SDS PAGE followed by western blot with 14928-1-AP (FAH antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

FAH Antibody in Western Blot (WB) — Mouse liver tissue were subjected to SDS PAGE followed by western blot with 14928-1-AP (FAH antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

Product Details

14928-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:1,000	View 2 publications 2 publications
Miscellaneous PubMed (Misc)	-	View 5 publications 5 publications

Product Specifications
Species Reactivity	Human, Mouse, Rat
Published species	Human
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	FAH Fusion Protein Ag6704 (70-419 aa encoded by BC002527) View antigen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.13 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C

Product Specific Information

Immunogen sequence: FMGLGQAAW KEARVFLQNL LSVSQARLRD DTELRKCAFI SQASATMHLP ATIGDYTDFY SSRQHATNVG IMFRDKENAL MPNWLHLPVG YHGRASSVVV SGTPIRRPMG QMKPDDSKPP VYGACKLLDM ELEMAFFVGP GNRLGEPIPI SKAHEHIFGM VLMNDWSARD IQKWEYVPLG PFLGKSFGTT VSPWVVPMDA LMPFAVPNPK QDPRPLPYLC HDEPYTFDIN LSVNLKGEGM SQAATICKSN FKYMYWTMLQ QLTHHSVNGC NLRPGDLLAS GTISGPEPEN FGSMLELSWK GTKPIDLGNG QTRKFLLDGD EVIITGYCQG DGYRIGFGQC AGKVLPALLP S (70-419 aa encoded by BC002527)

Target Information

This gene encodes the last enzyme in the tyrosine catabolism pathway. FAH deficiency is associated with Type 1 hereditary tyrosinemia (HT).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

BI2536, a potent and selective inhibitor of polo-like kinase 1, in combination with cisplatin exerts synergistic effects on gastric cancer cells.

International journal of oncology

Lian G,Li L,Shi Y,Jing C,Liu J,Guo X,Zhang Q,Dai T,Ye F,Wang Y,Chen M

Thu Mar 01 00:00:00 EST 2018

The screening and analysis of protein signatures and signaling associated with chemoresistance based on Protein Pathway Array technology in gastric cancer.

Oncology reports

Lian G,Li L,Ye F,Wang D,Liu J,Shi Y,Jing C,Suo J,Zhang DY,Chen M

Mon Jan 01 00:00:00 EST 2018

Protein Profiling of Bladder Urothelial Cell Carcinoma.

PloS one

Hu J,Ye F,Cui M,Lee P,Wei C,Hao Y,Wang X,Wang Y,Lu Z,Galsky M,McBride R,Wang L,Wang D,Cordon-Cardo C,Wang C,Zhang DY

Tue Aug 08 00:00:00 EDT 2017

Global profiling of the signaling network of papillary thyroid carcinoma.

Life sciences

Huang K,Cui M,Ye F,Li Y,Zhang D

Mon Feb 15 00:00:00 EST 2016

Protein marker profiling in different T classification in laryngeal squamous cell carcinoma.

Head & neck

Chen W,Ye F,Cui M,Sikora AG,Wang X,Wang P,Cui X,Guo X,Zhu W,Zhang DY

Sun Mar 01 00:00:00 EST 2015

Protein profiling of Helicobacter pylori-associated gastric cancer.

The American journal of pathology

Lian G,Wei C,Wang D,Cui M,Wang Z,Liu X,Li W,Wang L,Wang Q,Zhang DY,Suo J,Ye F

Thu May 01 00:00:00 EDT 2014

Protein predictive signatures for lymph node metastasis of gastric cancer.

International journal of cancer

Li W,Ye F,Wang D,Sun X,Tong W,Lian G,Jiang J,Suo J,Zhang DY

Mon Apr 15 00:00:00 EDT 2013

Bioinformatics

Protein Aliases: Beta-diketonase; FAA; Fumarylacetoacetase; Fumarylacetoacetate hydrolase; fumarylacetoacetate hydrolase (fumarylacetoacetase)

Gene Aliases: FAH

UniProt ID: (Human) P16930, (Rat) P25093, (Mouse) P35505

Entrez Gene ID: (Human) 2184, (Rat) 29383, (Mouse) 14085

arginine catabolic process L-phenylalanine catabolic process tyrosine catabolic process biological_process aromatic amino acid family metabolic process metabolic process

Process(es)

fumarylacetoacetase activity protein binding metal ion binding catalytic activity hydrolase activity