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Invitrogen
FAM111B Polyclonal Antibody
Advanced Verification
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
Product Details
PA5-58474
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human FAM111B. Recombinant protein control fragment (Product #RP-97540).
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2641223
Product Specific Information
Immunogen sequence: SMKTEENKSF SAMEDDQRTR PEVSKDTVMK QTHADTPVDH CLSGIRKCSS TFKLKSEVNK HETALEMQNP NLNNKECCFT FTLNGNS^M
^M
Highest antigen sequence identity to the following orthologs: Mouse - 27%, Rat - 24%.
Target Information
FAM111B is a 734 amino acid protein that is encoded by a gene that maps to human chromosome 11, which makes up around 4% of human genomic DNA and isconsidered a gene and disease association dense chromosome.The chromosome 11 encoded Atmgene isimportant for regulation ofcellcycle arrest and apoptosisfollowing double strand DNA breaks. Atmmutation leads to the disorderknown as ataxia-telangiectasia. The blood disorders Sickle cell anemia and beta thalassemia are caused by HBB genemutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associatedwithmutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associatedwith defectsin chromosome 11.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Cancer-associated nucleoprotein; family with sequence similarity 111, member B; Serine protease FAM111B
Gene Aliases: CANP; FAM111B; POIKTMP
UniProt ID: (Human) Q6SJ93
Entrez Gene ID: (Human) 374393
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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