This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%
FAM119A is a protein-lysine methyltransferase that selectively trimethylates residues in heat shock protein 70 (HSP70) family members. Contributes to the in vivo trimethylation of Lys residues in HSPA1 and HSPA8. In vitro methylates Lys-561 in HSPA1, Lys-564 in HSPA2, Lys-585 in HSPA5, Lys-563 in HSPA6 and Lys-561 in HSPA8.
Protein Aliases: family with sequence similarity 119, member A; heat shock protein 70kDa lysine (K) methyltransferase; Hepatocellular carcinoma-associated antigen 557b; HSPA lysine methyltransferase; HSPA-KMT; Methyltransferase-like protein 21A; Protein N-lysine methyltransferase METTL21A; protein-lysine methyltransferase METTL21A
Gene Aliases: FAM119A; HCA557B; HSPA-KMT; METTL21A
UniProt ID: (Human) Q8WXB1
Entrez Gene ID: (Human) 151194