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Abnova
FAM122A Polyclonal Antibody, MaxPab™
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Product Details
H00116224-B01P
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FAM122A (NP_612206.3, 1 a.a. approximately 287 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
50 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MAQEKMELDL ELPPGTGGSP AEGGGSGGGG GLRRSNSAPL IHGLSDTSPV FQAEAPSARR NSTTFPSRHG LLLPASPVRM HSSRLHQIKQ EEGMDLINRE TVHEREVQTA MQISHSWEES FSLSDNDVEK SASPKRIDFI PVSPAPSPTR GIGKQCFSPS LQSFVSSNGL PPSPIPSPTT RFTTRRSQSP INCIRPSVLG PLKRKCEMET EYQPKRFFQG ITNMLSSDVA QLSDPGVCVS SDTLDGNSSS AGSSCNSPAK VSTTTDSPVS PAQAASPFIP LDELSSK
Target Information
Acts as an inhibitor of serine/threonine-protein phosphatase 2A (PP2A) activity. Potentiates ubiquitin-mediated proteasomal degradation of serine/threonine-protein phosphatase 2A catalytic subunit alpha (PPP2CA). Inhibits PP2A-mediated dephosphorylation of WEE1, promoting ubiquitin- mediated proteolysis of WEE1, thereby releasing G2/M checkpoint.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: family with sequence similarity 122A; PABIR family member 1; PPP2R1A-PPP2R2A-interacting phosphatase regulator 1; protein FAM122A; unnamed protein product
Gene Aliases: C9orf42; FAM122A; PABIR1
UniProt ID: (Human) Q96E09
Entrez Gene ID: (Human) 116224
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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