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Invitrogen
FAM122B Polyclonal Antibody
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Product Details
PA5-34720
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human FAM122B. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.71 mg/mL
Amount
71 µg
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: A549, HeLa, HepG2, HCT116, mouse liver.
Predicted reactivity: Mouse (80%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
FAM122B (Family with Sequence Similarity 122 Member B) is a gene located on chromosome 9 that encodes a protein involved in cellular signaling and regulation. FAM122B is known to interact with protein phosphatase 2A (PP2A), a critical enzyme in multiple signaling pathways, thereby impacting various cellular functions such as growth, division, and apoptosis. This interaction is pivotal for the modulation of PP2A activity, which in turn influences numerous downstream signaling processes. Studies have indicated that FAM122B may play a role in cancer biology, particularly in the regulation of oncogenic pathways. Dysregulation of FAM122B expression has been observed in certain cancers, suggesting its potential involvement in tumor progression and as a biomarker for diagnosis or prognosis. Furthermore, the gene's expression patterns indicate its importance in normal cellular homeostasis and the maintenance of cellular signaling balance.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: erg-3; ets-related; family with sequence similarity 122B; p55; PABIR family member 2; protein FAM122B; synoviocyte proliferation associated in collagen-induced arthritis 2; TMPRSS2/ERG fusion; unnamed protein product
Gene Aliases: 4632404H22Rik; AI256344; FAM122B; PABIR2; SPACIA2
UniProt ID: (Mouse) Q6NZE7, (Human) Q7Z309
Entrez Gene ID: (Mouse) 78755, (Human) 159090
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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