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Product Details
25816-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FAM125A Fusion Protein Ag22919 (1-214 aa encoded by BC007883)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MDPVPGTDS APLAGLAWSS ASAPPPRGFS AISCTVEGAP ASFGKSFAQK SGYFLCLSSL GSLENPQENV VADIQIVVDK SPLPLGFSPV CDPMDSKASV SKKKRMCVKL LPLGATDTAV FDVRLSGKTK TVPGYLRIGD MGGFAIWCKK AKAPRPVPKP RGLSRDMQGL SLDAASQPSK GGLLERTASR LGSRASTLRR NDSIYEASSL YGISA (1-214 aa encoded by BC007883)
Target Information
FAM125A, also named as MVB12A and CFBP, is a component of the ESCRT-I complex. FAM125A is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. FAM125A has three isoforms with MW 27-28 kDa and 25 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CIN85/CD2AP family binding protein; CIN85/CD2AP family-binding protein; ESCRT-I complex subunit MVB12A; family with sequence similarity 125, member A; Multivesicular body subunit 12A; Protein FAM125A
Gene Aliases: CFBP; FAM125A; MVB12A
UniProt ID: (Human) Q96EY5
Entrez Gene ID: (Human) 93343
autophagy
protein transport
virus maturation
multivesicular body assembly
viral budding via host ESCRT complex
regulation of epidermal growth factor receptor signaling pathway
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
positive regulation of viral process
regulation of viral budding via host ESCRT complex
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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