Immunogen sequence: DAHMTWLNFV RRPDDGALRK RCGSRDKKPR DLFGPPGPPG AEVTAETLLH EFQELLKEAT ERRFSGLLD
Highest antigen sequence identity to the following orthologs: Mouse - 65%, Rat - 65%.
Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses de novo glucose production in hepatocytes via the PI3K-Akt signaling pathway. Administration lead to reduction of blood glucose. Able to attenuate inflammation in fat tissue. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Adipolin; Adipolin cleaved form; Adipolin fC1QTNF12; Adipolin fCTRP12; Adipolin full-length form; Adipolin gC1QTNF12; Adipolin gCTRP12; Adipose-derived insulin-sensitizing factor; C1q and TNF related protein 12; C1q domain containing 2; C1q/TNF-related protein 12; Complement C1q tumor necrosis factor-related protein 12; family with sequence similarity 132, member A; protein FAM132A
Gene Aliases: C1QDC2; C1QTNF12; CTRP12; FAM132A
UniProt ID: (Human) Q5T7M4
Entrez Gene ID: (Human) 388581
Molecular Function: peptide hormone