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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • FAM13B Antibodies

          Invitrogen

          FAM13B Polyclonal Antibody

          View all (4) FAM13B antibodies

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          Cite FAM13B Polyclonal Antibody

          • Antibody Testing Data (1)
          FAM13B Antibody in Immunocytochemistry (ICC/IF)
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          FAM13B Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          FAM13B Antibody (PA5-65314) in ICC/IF

          Immunofluorescent staining of FAM13B in human cell line U-2 OS shows localization to nucleoplasm. Samples were probed using a FAM13B Polyclonal Antibody (Product # PA5-65314). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          FAM13B Antibody in Immunocytochemistry (ICC/IF)
          FAM13B Polyclonal Antibody

          Product Details

          PA5-65314

          Applications
          Tested Dilution
          Publications

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant Human FAM13B. Recombinant protein control fragment (Product #RP-106016).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.2 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2664979

          Product Specific Information

          Immunogen sequence: SPSLSNCNSVL ANKIFGIPLD ELQQGGHPDN EVPFIVRHVV DYIEEHGGLE QQGLFQVNGN AETVEWLRQR YDSGEEVDLV KEADVPSAI

          Highest antigen sequence identity to the following orthologs - mouse 98%, rat 98%.

          Target Information

          FAM13B is a 915 amino acid protein that is encoded by a gene that maps to human chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: family with sequence similarity 13, member B; family with sequence similarity 13, member B1; GAP-like protein N61; Protein FAM13B

          View more View less

          Gene Aliases: ARHGAP49; C5orf5; FAM13B; FAM13B1; KHCHP; N61

          View more View less

          UniProt ID: (Human) Q9NYF5

          View more View less

          Entrez Gene ID: (Human) 51306

          View more View less

          Function(s)
          GTPase activator activity
          Process(es)
          positive regulation of defense response to virus by host signal transduction positive regulation of GTPase activity regulation of small GTPase mediated signal transduction mitophagy in response to mitochondrial depolarization xenophagy
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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