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Product Details
PA5-58953
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human FAM149B1. Recombinant protein control fragment (Product #RP-97086).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2641272
Product Specific Information
Immunogen sequence: DDKLLMRPGS STILSTRNWP NRAVEFSTSS LSYTVQSTRR RNPPPRTLHP ISTSHSCAET PRSVEEILRG ARVPVAPDSL SSPSP
Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 79%.
Target Information
Involved in cilium assembly and protein localization to cilium. Predicted to be located in cilium. Implicated in Joubert syndrome. FAM149B1 (Family With Sequence Similarity 149 Member B1) is a Protein Coding gene. Diseases associated with FAM149B1 include Joubert Syndrome 36 and Orofaciodigital Syndrome Vi. An important paralog of this gene is FAM149A. Involved in the localization of proteins to the cilium and cilium assembly. Indirectly regulates the signaling functions of the cilium, being required for normal SHH/smoothened signaling and proper development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: family with sequence similarity 149, member B1; Primary cilium assembly protein FAM149B1
Gene Aliases: FAM149B1; KIAA0974
UniProt ID: (Human) Q96BN6
Entrez Gene ID: (Human) 317662
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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