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Invitrogen
FAM3B Polyclonal Antibody
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Product Details
PA5-102346
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human FAM3B(Accession P58499), corresponding to amino acid residues S187-S235.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total FAM3B.
Target Information
FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11 or PANDER, is a 235 amino acid secreted protein that localizes to discrete vesicular and perinuclear structures. Expressed at high levels in pancreas and at lower levels in kidney, colon, testis, prostate and small intestine, FAM3B functions as an islet-specific cytokine that promotes apoptosis and may inhibit Insulin secretion from beta-cells, possibly playing a role in overall pancreatic activity. Human FAM3B shares 78% sequence identity with its mouse counterpart, suggesting a conserved role between species. Three isoforms of FAM3B, designated A, B and C, exist due to alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 21-Feb; Cytokine-like protein 2-21; D21M16SJHU19e; family with sequence similarity 3, member B; pancreatic derived factor; Pancreatic-derived factor; PANDER; Protein FAM3B
Gene Aliases: 2-21; 9030624C24Rik; C21orf11; C21orf76; D16Jhu19e; FAM3B; ORF9; PANDER; PRED44; RGD1311662; UNQ320/PRO365
UniProt ID: (Human) P58499, (Mouse) Q9D309
Entrez Gene ID: (Human) 54097, (Mouse) 52793, (Rat) 304050
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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