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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A 19 amino acid peptide from near the carboxy terminus of human FAM59B.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Immunocytochemistry (ICC)||20 ug/ml|
|Immunofluorescence (IF)||20 ug/ml|
|Immunohistochemistry (IHC)||5 µg/ml|
|Western Blot (WB)||1 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
A suggested positive control is SK-N-SH cell lysate.
PA5-20846 can be used with blocking peptide PEP-0960.
FAM59B is related to the FAM59A protein (also known as GAREM). While little is known of the role of the FAM59B protein, FAM59A is a downstream molecule in the EGF signaling pathway and binds Grb2, an adaptor protein crucial to the transduction of growth signals from the plasma membrane to the nucleus. Like FAM59A, FAM59B may play a role in ligand-mediated signaling pathway of the EGF receptor and the tumorigenesis of cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
family with sequence similarity 59, member B; GRB2 associated regulator of MAPK1 2; GRB2 associated, regulator of MAPK1-like; GRB2-associated and regulator of MAPK protein-like; GRB2-associated and regulator of MAPK1-like; HRIHFB2063; protein FAM59B
FAM59B; GAREM2; GAREML; Gm444; HRIHFB2063; KIAA2038