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Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Deubiquitinating enzyme MINDY-1; family with sequence similarity 63 member A; MINDY deubiquitinase 1; MIU-containing novel DUB family member 1; motif interacting with Ub-containing novel DUB; NF-E2 inducible protein; Protein FAM63A; RP11-316M1.5; Ubiquitin carboxyl-terminal hydrolase MINDY-1; unnamed protein product
Gene Aliases: 1810005H09Rik; 4930504E06Rik; AA562754; AA960384; AW561904; cI-40; FAM63A; KIAA1390; MINDY-1; MINDY1; mKIAA1390; Ni
UniProt ID: (Mouse) Q76LS9, (Rat) Q5BJQ2, (Human) Q8N5J2
Entrez Gene ID: (Mouse) 75007, (Rat) 310665, (Human) 55793
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