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Invitrogen
FAM73A Polyclonal Antibody
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Product Details
PA5-32001
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human FAM73A. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: U87-MG.
Predicted reactivity: Mouse (86%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The FAM73A gene, also known as Family With Sequence Similarity 73 Member A, is located on chromosome 2q33.3. This gene encodes a protein embedded in cellular membranes and is recognized for its involvement in various cellular processes including signal transduction and cell communication. FAM73A has been observed to play a significant role in the regulation of cancer stem cell-like properties, particularly in gastric cancer, where its circular RNA form (circFAM73A) has been implicated in tumor progression. Additionally, FAM73A is involved in iron homeostasis and resistance mechanisms within the cell, suggesting its participation in broader metabolic and stress response pathways. The gene includes multiple exons and is subject to alternative splicing, which yields various transcript variants, enhancing its functional diversity within different cellular contexts.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: family with sequence similarity 73 member A; family with sequence similarity 73, member A; Mitoguardin 1; Protein FAM73A
Gene Aliases: FAM73A; MIGA1
UniProt ID: (Human) Q8NAN2
Entrez Gene ID: (Human) 374986
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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