Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: ASSTGSPASI RTTDFHNPGY PKYLGTPHLE LYLSDSLRNL NKERQFHFAG IRSRLNHMLA MLSRRTLFTE NHLGLHSGNF S
Probable proto-oncogene that regulates cell proliferation, growth, migration and epithelial to mesenchymal transition. Through the degradation of FBXW7, may act indirectly on the expression and downstream signaling of MTOR, JUN and MYC (PubMed:24344117). May play also a role in cell proliferation through activation of the ERK1/ERK2 signaling cascade (PubMed:25646692). May also be important for proper chromosome congression and alignment during mitosis through its interaction with KIF22.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: family with sequence similarity 83, member D; Protein FAM83D; Spindle protein CHICA
Gene Aliases: C20orf129; CHICA; dJ616B8.3; FAM83D
UniProt ID: (Human) Q9H4H8
Entrez Gene ID: (Human) 81610
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