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Proteintech
FANCA Polyclonal Antibody
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Product Details
11975-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FANCA Fusion Protein Ag2598 (1-297 aa encoded by BC008979)
Conjugate
Form
Liquid
Concentration
0.31 mg/mL
Amount
46.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSDSWVPNS ASGQDPGGRR RAWAELLAGR VKREKYNPER AQKLKESAVR LLRSHQDLNA LLLEVEGPLC KKLSLSKVID CDSSEAYANH SSSFIGSALQ DQASRLGVPV GILSAGMVAS SVGQICTAPA ETSHPVLLTV EQRKKLSSLL EFAQYLLAHS MFSRLSFCQE LWKIQSSLLL EAVWHLHVQG IVSLQELLES HPDMHAVGSW LFRNLCCLCE QMEASCQHAD VARAMLSDFV QMFVLRGFQK NSDLRRTVEP EKMPQVAVDV LQRMLIFALD ALAAGVQEES STHKIVRC (1-297 aa encoded by BC008979)
Target Information
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. The encoded protein is also a substrate for ubiquitin-E3-ligase parkin. The gene has previously been referred to as synaptotagmin XII but has been renamed synaptotagmin XI to be consistent with mouse and rat official nomenclature.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Fanconi anemia complementation group A; Fanconi anemia group A protein; Fanconi anemia, complementation group H; Fanconi anemia, type 1; Protein FACA; unnamed protein product
Gene Aliases: FA; FA-H; FA1; FAA; FACA; FAH; FANCA; FANCH
UniProt ID: (Human) Q92497
Entrez Gene ID: (Human) 2175
DNA repair
cellular response to DNA damage stimulus
male meiosis
male gonad development
female gonad development
interstrand cross-link repair
regulation of regulatory T cell differentiation
regulation of inflammatory response
protein-containing complex assembly
regulation of germ cell proliferation
regulation of CD40 signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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