This Antibody was verified by Knockout to ensure that the antibody binds to the antigen stated. View Details
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group I. Alternative splicing results in two transcript variants encoding different isoforms.
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Protein Aliases: Fanconi anemia group I protein; Fanconi anemia, complementation group I; Protein FACI
Gene Aliases: FANCI; KIAA1794
UniProt ID: (Human) Q9NVI1
Entrez Gene ID: (Human) 55215