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Invitrogen
FAPP2 Polyclonal Antibody
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Product Details
PA5-113305
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Pleckstrin homology domain-containing family A member 8 protein (1-300AA)
Conjugate
Form
Liquid
Concentration
1.5 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Cargo transport protein that is required for apical transport from the Golgi complex. Transports AQP2 from the trans-Golgi network (TGN) to sites of AQP2 phosphorylation. Mediates the non-vesicular transport of glucosylceramide (GlcCer) from the trans-Golgi network (TGN) to the plasma membrane and plays a pivotal role in the synthesis of complex glycosphingolipids. Binding of both phosphatidylinositol 4-phosphate (PIP) and ARF1 are essential for the GlcCer transfer ability. Also required for primary cilium formation, possibly by being involved in the transport of raft lipids to the apical membrane, and for membrane tubulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FAPP-2; FAPP2; hFAPP2; MGC3358; PH domain-containing family A member 8; phosphatidylinositol 4-phosphate adaptor protein-2; Phosphatidylinositol-four-phosphate adapter protein 2; phosphoinositol 4-phosphate adapter protein 2; pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8; Pleckstrin homology domain-containing family A member 8; Serologically defined breast cancer antigen NY-BR-86; unnamed protein product
Gene Aliases: 6330400G01; AA517676; BC052360; Fapp-2; FAPP2; PLEKHA8
UniProt ID: (Human) Q96JA3, (Mouse) Q80W71
Entrez Gene ID: (Human) 84725, (Mouse) 231999
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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