Immunogen sequence: FLGKVLMEKL FRTSPDLKVI YILVRPKAGQ TLQQRVFQIL DSKLFEKVKE VCPNVHEKIR AIYADLNQND FAISKEDMQE LLSCTNIIFH CAATVRFDD
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 90%.
This gene belongs to the short chain dehydrogenase/reductase superfamily. It encodes a reductase enzyme involved in the first step of wax biosynthesis wherein fatty acids are converted to fatty alcohols. The encoded peroxisomal protein utilizes saturated fatty acids of 16 or 18 carbons as preferred substrates. Alternatively spliced transcript variants have been observed for this gene. Related pseudogenes have been identified on chromosomes 2, 14 and 22.
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Protein Aliases: epididymis secretory protein Li 81; fatty acyl CoA reductase 2; Fatty acyl-CoA reductase 2; Male sterility domain-containing protein 1; short chain dehydrogenase/reductase family 10E, member 2
Gene Aliases: FAR2; HEL-S-81; MLSTD1; SDR10E2
UniProt ID: (Human) F8VV73
Entrez Gene ID: (Human) 55711