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Immunogen sequence: DHSRITVNT RNIFIECTGT DFTKAKIVLD IIVTMFSEYC ENQFTVEAAE VVFPNGKSHT FPELAYRKEM VRADLINKKV GIRETPENLA KLLTRMYLKS EVIGDGNQIE IEIPPTRADI IHACDIVEDA AIAYGYNNIQ MTLPKTYTIA NQFPLNKLTE LLRHDMAAAG FTEALTFALC SQEDIADKLG VDISATKAVH ISNPKTAEFQ VARTTLLPGL LKTIAANRKM PLPLKLFEIS DIVIKDSNTD VGAKNYRHLC AVYYNKNPGF EIIHGLLDRI MQLLDVPPGE DKGGYVIKAS EGPAFFPGRC AEIFARGQSV GKLGVLHPDV ITKFELTMPC SSLEINIGPF L (240-589 aa encoded by BC017783)
This gene encodes a highly conserved enzyme that belongs to the aminoacyl-tRNA synthetase class IIc subfamily. This enzyme comprises the regulatory beta subunits that form a tetramer with two catalytic alpha subunits. In the presence of ATP, this tetramer is responsible for attaching L-phenylalanine to the terminal adenosine of the appropriate tRNA. A pseudogene located on chromosome 10 has been identified.
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Protein Aliases: ph; phenylalanine tRNA ligase 1, beta, cytoplasmic; phenylalanine tRNA synthetase alpha; phenylalanine--tRNA ligase beta chain; Phenylalanine--tRNA ligase beta subunit; phenylalanine-tRNA ligase beta chain; phenylalanine-tRNA synthetase-like, beta subunit; phenylalanyl-tRNA synthetase beta chain; Phenylalanyl-tRNA synthetase beta subunit; phenylalanyl-tRNA synthetase beta-subunit; phenylalanyl-tRNA synthetase, beta subunit; phenylalanyl-tRNA synthetase-like, beta subunit; PheRS; PheRS alpha
Gene Aliases: C76708; Farsa; FARSB; Farsl; FARSLB; FRSB; HSPC173; PheHB; PheRS
Molecular Function: aminoacyl-tRNA synthetase