This gene encodes a highly conserved enzyme that belongs to the aminoacyl-tRNA synthetase class IIc subfamily. This enzyme comprises the regulatory beta subunits that form a tetramer with two catalytic alpha subunits. In the presence of ATP, this tetramer is responsible for attaching L-phenylalanine to the terminal adenosine of the appropriate tRNA. A pseudogene located on chromosome 10 has been identified.
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Protein Aliases: ph; phenylalanine tRNA ligase 1, beta, cytoplasmic; phenylalanine tRNA synthetase alpha; phenylalanine--tRNA ligase beta chain; Phenylalanine--tRNA ligase beta subunit; phenylalanine-tRNA ligase beta chain; phenylalanine-tRNA synthetase-like, beta subunit; phenylalanyl-tRNA synthetase beta chain; Phenylalanyl-tRNA synthetase beta subunit; phenylalanyl-tRNA synthetase beta-subunit; phenylalanyl-tRNA synthetase, beta subunit; phenylalanyl-tRNA synthetase-like, beta subunit; PheRS; PheRS alpha
Gene Aliases: C76708; Farsa; FARSB; Farsl; FARSLB; FRSB; HSPC173; PheHB; PheRS