Search
Abnova
FASN Polyclonal Antibody, MaxPab™
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 1
FASN Antibody (H00002194-D01P) in WB
Western Blot analysis of FASN expression in transfected 293T cell line (H00002194-T01) by FASN MaxPab polyclonal antibody.
Lane 1: FASN transfected lysate(48.30 KDa).
Lane 2: Non-transfected lysate.
Lane 1: FASN transfected lysate(48.30 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00002194-D01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FASN (AAH07909.1, 1 a.a. approximately 439 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MSTNDTIVSG TLPQRMASCL EVLDLFLNQP HMVLSSFVLA EKAAAYRDRD SQRDLVEAVA HILGIRDLAA VNLDSSLADL GLDSLMSVEV RQTLERELNL VLSVREVRQL TLRKLQELSS KADEASELAC PTPKEDGLAQ QQTQLNLRSL LVNPEGPTLM RLNSVQSSER PLFLVHPIEG STTVFHSLAS RLSIPTYGLQ CTRAAPLDSI HSLAAYYIDC IRQVQPEGPY RVAGYSYGAC VAFEMCSQLQ AQQSPAPTHN SLFLFDGSPT YVLAYTQSYR AKLTPGCEAE AETEAICFFV QQFTDMEHNR VLEALLPLKG LEERVAAAVD LIIKSHQGLD RQELSFAARS FYYKLRAAEQ YTPKAKYHGN VMLLRAKTGG AYGEDLGADY NLSQVCDGKV SVHVIEGDHR TLLEGSGLES IISIIHSSLA EPRVSVREG
Target Information
Fatty acid synthase is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; 3-oxoacyl-[acyl-carrier-protein] reductase; 3-oxoacyl-[acyl-carrier-protein] synthase; [Acyl-carrier-protein] S-acetyltransferase; [Acyl-carrier-protein] S-malonyltransferase; Acyl-[acyl-carrier-protein] hydrolase; encodes region of fatty acid synthase activity; FAS; multifunctional protein; Enoyl-[acyl-carrier-protein] reductase; FAS; Fatty acid synthase; MGC14367; MGC15706; short chain dehydrogenase/reductase family 27X, member 1; Type I fatty acid synthase
Gene Aliases: FAS; FASN; OA-519; SDR27X1
UniProt ID: (Human) P49327
Entrez Gene ID: (Human) 2194
RNA binding
catalytic activity
fatty acid synthase activity
[acyl-carrier-protein] S-acetyltransferase activity
[acyl-carrier-protein] S-malonyltransferase activity
3-oxoacyl-[acyl-carrier-protein] synthase activity
3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
protein binding
acyl-[acyl-carrier-protein] hydrolase activity
oxidoreductase activity
transferase activity
transferase activity, transferring acyl groups
hydrolase activity
lyase activity
3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
phosphopantetheine binding
identical protein binding
cadherin binding
enoyl-[acyl-carrier-protein] reductase (NADPH) activity
osteoblast differentiation
epithelial cell development
acetyl-CoA metabolic process
lipid metabolic process
fatty acid metabolic process
fatty acid biosynthetic process
inflammatory response
response to nutrient
lipid biosynthetic process
ether lipid biosynthetic process
tissue development
neutrophil differentiation
monocyte differentiation
mammary gland development
response to nutrient levels
modulation by host of viral process
fatty-acyl-CoA biosynthetic process
response to caloric restriction
cellular response to interleukin-4
establishment of endothelial intestinal barrier
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support