Invitrogen

FASN Polyclonal Antibody

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FASN Antibody in Western Blot (WB) — Western blot analysis of Mouse Brain Tissue Lysate using Product # PA5-19509, Fatty Acid Synthase primary antibody at a dilution of 1 µg/mL. Blot treated with a secondary HRP-conjugated Goat polyclonal anti-Rabbit antibody was used at a dilution of 1:3000.

Product Details

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC)

1 µg/mL

Immunofluorescence (IF)

1 µg/mL

Immunohistochemistry (Frozen) (IHC (F))

Assay-Dependent

Immunohistochemistry (Paraffin) (IHC (P))

Assay-Dependent

Immunohistochemistry (PFA fixed) (IHC (PFA))

2 µg/mL

Immunoprecipitation (IP)

Assay-Dependent

Western Blot (WB)

Assay-Dependent

Product Specifications

Species

Human, Mouse, Rat

Expression System

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide conjugated to KLH derived from within residues 2450 to the C-terminus of Mouse Fatty Acid Synthase.

Conjugate

Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.4, with 1% BSA

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

RRID

AB_10985006

Product Specific Information

This antibody is predicted to react with chicken and cow based on sequence homology.

Target Information

Fatty acid synthase is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; 3-oxoacyl-[acyl-carrier-protein] reductase; 3-oxoacyl-[acyl-carrier-protein] synthase; [Acyl-carrier-protein] S-acetyltransferase; [Acyl-carrier-protein] S-malonyltransferase; Enoyl-[acyl-carrier-protein] reductase; Fatty acid synthase; MGC14367; MGC15706; Oleoyl-[acyl-carrier-protein] hydrolase; short chain dehydrogenase/reductase family 27X, member 1

Gene Aliases: A630082H08Rik; FAS; FASN; OA-519; SDR27X1

UniProt ID: (Human) P49327, (Mouse) P19096, (Rat) P12785

Entrez Gene ID: (Human) 2194, (Mouse) 14104, (Rat) 50671

Molecular Function: acyltransferase dehydrogenase esterase hydrolase ligase methyltransferase oxidoreductase transferase