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Bioss

FASN/Fatty Acid Synthase Polyclonal Antibody

View all (31) FASN antibodies
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Product Details

BS-1498R

Applications Tested Dilution Publications

Western Blot (WB)

 1:300-1:1,000 -

Immunohistochemistry (Paraffin) (IHC (P))

 1:200 -

Immunohistochemistry (Frozen) (IHC (F))

 1:100-1:500 -

Immunocytochemistry (ICC/IF)

 1:50-1:200 -

ELISA (ELISA)

 1:500-1:1,000 -
Product Specifications

Species Reactivity

 Human, Mouse, Rat

Host/Isotype

 Rabbit / IgG

Class

 Polyclonal

Type

 Antibody

Immunogen

KLH conjugated synthetic peptide derived from mouse FASN, amino acids 651-750.
View antigen

Conjugate

 Unconjugated

Form

 Liquid

Concentration

 1 mg/mL

Purification

 Protein A

Storage buffer

 PBS with 1% BSA, 50% glycerol

Contains

 0.09% sodium azide

Storage conditions

 -20°C

Target Information

Fatty acid synthase is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; 3-oxoacyl-[acyl-carrier-protein] reductase; 3-oxoacyl-[acyl-carrier-protein] synthase; [Acyl-carrier-protein] S-acetyltransferase; [Acyl-carrier-protein] S-malonyltransferase; Acyl-[acyl-carrier-protein] hydrolase; Enoyl-[acyl-carrier-protein] reductase; Fatty acid synthase; MGC14367; MGC15706; short chain dehydrogenase/reductase family 27X, member 1; Type I FAS; Type I Fatty Acid Synthase

Gene Aliases: A630082H08Rik; FAS; FASN; OA-519; SDR27X1

UniProt ID: (Human) P49327, (Mouse) P19096, (Rat) P12785

Entrez Gene ID: (Human) 2194, (Mouse) 14104, (Rat) 50671

Function(s)
osteoblast differentiation acetyl-CoA metabolic process fatty acid metabolic process fatty acid biosynthetic process pantothenate metabolic process mammary gland development positive regulation of cellular metabolic process long-chain fatty-acyl-CoA biosynthetic process oxidation-reduction process cellular response to interleukin-4 cell-cell adhesion lipid metabolic process metabolic process biosynthetic process lipid biosynthetic process
Process(es)
fatty acid synthase activity [acyl-carrier-protein] S-acetyltransferase activity [acyl-carrier-protein] S-malonyltransferase activity 3-oxoacyl-[acyl-carrier-protein] synthase activity 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity oleoyl-[acyl-carrier-protein] hydrolase activity protein binding drug binding myristoyl-[acyl-carrier-protein] hydrolase activity palmitoyl-[acyl-carrier-protein] hydrolase activity phosphopantetheine binding protein homodimerization activity poly(A) RNA binding enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity NADPH binding cadherin binding involved in cell-cell adhesion 3-oxo-pimeloyl-[acp] methyl ester reductase activity catalytic activity zinc ion binding acyl-[acyl-carrier-protein] hydrolase activity oxidoreductase activity transferase activity hydrolase activity hydrolase activity, acting on ester bonds lyase activity 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity identical protein binding

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