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Immunogen sequence: METLPDTMAAG ALQRICEVEK KDGDQGLPKE ILENSIFQAL CFQFEKEPSQ LSNTSLVTAL QALILLHVDP QSSLLLNLVA ECQNRLRKGG MEVRNLCILG ESLITLHSSG CVTLELIINQ LQG
Highest antigen sequence identity to the following orthologs - mouse 56%, rat 57%.
This gene encodes a member of a small family of Fas-activated serine/threonine kinase domain (FASTKD) containing proteins that share an amino terminal mitochondrial targeting domain and multiple carboxy terminal FAST domains as well as a putative RNA-binding RAP domain. The members of this family are ubiquitously expressed and are generally most abundant in mitochondria-enriched tissues such as heart, skeletal muscle and brown-adipose tissue. Some members of this protein family may play a role in apoptosis. The protein encoded by this gene interacts with components of the mitochondrial respiratory and translation networks. A pseudogene of this gene is also present on chromosome 5. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FAKD3; FAST kinase domain-containing protein 3; FAST kinase domain-containing protein 3, mitochondrial; FLJ23274
Gene Aliases: FASTKD3
UniProt ID: (Human) Q14CZ7
Entrez Gene ID: (Human) 79072
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