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Proteintech
FBP1 Polyclonal Antibody
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Product Details
12842-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Pig
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FBP1 Fusion Protein Ag3837 (1-338 aa encoded by BC012927)
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MADQAPFDT DVNTLTRFVM EEGRKARGTG ELTQLLNSLC TAVKAISSAV RKAGIAHLYG IAGSTNVTGD QVKKLDVLSN DLVMNMLKSS FATCVLVSEE DKHAIIVEPE KRGKYVVCFD PLDGSSNIDC LVSVGTIFGI YRKKSTDEPS EKDALQPGRN LVAAGYALYG SATMLVLAMD CGVNCFMLDP AIGEFILVDK DVKIKKKGKI YSLNEGYARD FDPAVTEYIQ RKKFPPDNSA PYGARYVGSM VADVHRTLVY GGIFLYPANK KSPNGKLRLL YECNPMAYVM EKAGGMATTG KEAVLDVIPT DIHQRAPVIL GSPDDVLEFL KVYEKHSAQ (1-338 aa encoded by BC012927 )
Target Information
Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: D-fructose-1,6-bisphosphate 1-phosphohydrolase 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase 3; EC 3.1.3.11; FBP 1; FBPase 1; FBPase 3; FBPase brain isoform; FBPase liver; fructose-1; fructose-1,6- biphosphatase 1; Fructose-1,6-bisphosphatase 1; Fructose-1,6-bisphosphatase isozyme 3; Fructose-16- biphosphatase; growth-inhibiting protein 17; Liver FBPase
Gene Aliases: FBP; Fbp-2; FBP1; Fbp2; Fbp3; Fdp
UniProt ID: (Human) P09467, (Rat) P19112, (Mouse) Q9QXD6
Entrez Gene ID: (Human) 2203, (Rat) 24362, (Mouse) 14121
fructose metabolic process
fructose catabolic process
fructose 6-phosphate metabolic process
gluconeogenesis
regulation of gluconeogenesis
dephosphorylation
negative regulation of cell growth
cellular response to drug
negative regulation of glycolytic process
negative regulation of Ras protein signal transduction
protein homotetramerization
cellular response to magnesium ion
carbohydrate metabolic process
cellular response to insulin stimulus
metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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