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Proteintech
FBX4 Polyclonal Antibody
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Product Details
13855-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FBX4 fusion protein Ag4829
Conjugate
Form
Liquid
Concentration
300 µg/mL
Amount
45 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Sequence of this protein is as follows: MAGSEPRSGT NSPPPPFSDW GRLEAAILSG WKTFWQSVSK ERVARTTSRE EVDEAASTLT RLPIDVQLYI LSFLSPHDLC QLGSTNHYWN ETVRDPILWR YFLLRDLPSW SSVDWKSLPD LEILKKPISE VTDGAFFDYM AVYRMCCPYT RRASKSSRPM YGAVTSFLHS LIIQNEPRFA MFGPGLEELN TSLVLSLMSS EELCPTAGLP QRQIDGIGSG VNFQLNNQHK FNILILYSTT RKERDRAREE HTSAVNKMFS RHNEGDDQQG SRYSVIPQIQ KVCEVVDGFI YVANAEAHKR HEWQDEFSHI MAMTDPAFGS SGRPLLVLSC ISQGDVKRMP CFYLAHELHL NLLNHPWLVQ DTEAETLTGF LNGIEWILEE VESKRAR
Target Information
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: F-box only protein 4; F-box protein Fbx4; unnamed protein product
Gene Aliases: FBX4; FBXO4
UniProt ID: (Human) Q9UKT5
Entrez Gene ID: (Human) 26272
protein polyubiquitination
telomere maintenance
cytoplasmic translational initiation
ubiquitin-dependent protein catabolic process
regulation of macromolecule biosynthetic process
posttranscriptional regulation of gene expression
protein ubiquitination
cellular homeostasis
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
positive regulation of protein ubiquitination
regulation of protein stability
protein destabilization
positive regulation of telomere maintenance via telomerase
common myeloid progenitor cell proliferation
positive regulation of translation
negative regulation of fibroblast proliferation
cellular response to ionizing radiation
cellular senescence
membraneless organelle assembly
negative regulation of protein localization to nucleus
positive regulation of protein polyubiquitination
regulation of DNA damage checkpoint
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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